Takasaki University of Health and Welfare

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HONMA Shigeyoshi

Profile Research field Research achievement Educational achievement Management achievement Social contribution achievement

 

Published Papers
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI 
1
Prevention of Renal Interstitial Fibrosis by Suplatast in a Mouse Model. , Biological & pharmaceutical bulletin, 46( 1), 61- 66, 2023, https://doi.org/10.1248/bpb.b22-00554 
2
Effect of N-Acetyl Cysteine on Renal Interstitial Fibrosis in Mice. , Biological & pharmaceutical bulletin, 43( 12), 1940- 1944, 2020, https://doi.org/10.1248/bpb.b20-00657 
3
Dimethylthiourea ameliorates carbon tetrachloride-induced acute liver injury in ovariectomized mice. , Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 104,  427- 436, Aug. 2018, https://doi.org/10.1016/j.biopha.2018.05.065 
4
Effect of brefelamide on proliferation of 1321N1 human astrocytoma cells induced by glial cell line-derived neurotrophic factor , Pharmazie, 73( 1), 22- 28, 2018, https://doi.org/10.1691/ph.2018.7786 
5
Effect of brefelamide on HGF-induced survival of 1321N1 human astrocytoma cells , IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 52( 6), 705- 711, Jun. 2016, https://doi.org/10.1007/s11626-016-0019-z 
6
Effect of amlodipine on mouse renal interstitial fibrosis , EUROPEAN JOURNAL OF PHARMACOLOGY, 780,  136- 141, Jun. 2016, https://doi.org/10.1016/j.ejphar.2016.03.041 
7
Apocynin reduced doxycycline-induced acute liver injury in ovariectomized mice , Toxicology Reports, 3,  357- 363, 2016, https://doi.org/10.1016/j.toxrep.2016.02.003 
8
Effect of cyclooxygenase (COX)-2 inhibition on mouse renal interstitial fibrosis , EUROPEAN JOURNAL OF PHARMACOLOGY, 740,  578- 583, Oct. 2014, https://doi.org/10.1016/j.ejphar.2014.06.027 
9
Regeneration of Injured Renal Tubules , JOURNAL OF PHARMACOLOGICAL SCIENCES, 124( 2), 117- 122, Feb. 2014, https://doi.org/10.1254/jphs.13R12CP 
10
Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor , EUROPEAN JOURNAL OF PHARMACOLOGY, 715( 1-3), 181- 188, Sep. 2013, https://doi.org/10.1016/j.ejphar.2013.05.023 
11
Interleukin-6 modulates oxidative stress produced during the development of cisplatin nephrotoxicity , LIFE SCIENCES, 92( 12), 694- 700, Apr. 2013, https://doi.org/10.1016/j.lfs.2013.01.026 
12
Interleukin-6 plays a protective role in development of cisplatin-induced acute renal failure through upregulation of anti-oxidative stress factors , LIFE SCIENCES, 88( 25-26), 1142- 1148, Jun. 2011, https://doi.org/10.1016/j.lfs.2011.04.016 
13
A reduction of epidermal growth factor receptor is involved in brefelamide-induced inhibition of phosphorylation of ERK in human astrocytoma cells , EUROPEAN JOURNAL OF PHARMACOLOGY, 616( 1-3), 38- 42, Aug. 2009, https://doi.org/10.1016/j.ejphar.2009.06.030 
14
Distinct effects of Z-335, a new thromboxane A(2) receptor antagonist, on rabbit platelets and aortic smooth muscle , PHARMACOLOGY, 79( 1), 50- 56, 2007, https://doi.org/10.1159/000097632 
15
Thromboxane A(2) receptor-mediated G(12/13)-dependent glial morphological change , EUROPEAN JOURNAL OF PHARMACOLOGY, 545( 2-3), 100- 108, Sep. 2006, https://doi.org/10.1016/j.ejphar.2006.06.062 
16
The isolation and synthesis of two novel N-acetyl glucosamine derivatives from Dictyostelium cellular slime molds which exhibit neurite outgrowth activity , TETRAHEDRON LETTERS, 43( 8), 1477- 1480, Feb. 2002,  
17
Furanodictine A and B: Amino sugar analogues produced by cellular slime mold Dictyostelium discoideum showing neuronal differentiation activity , JOURNAL OF ORGANIC CHEMISTRY, 66( 21), 6982- 6987, Oct. 2001,  
18
Involvement of phosphatidylcholine-specific phospholipase C in thromboxane A(2)-induced activation of mitogen-activated protein kinase in astrocytoma cells , JOURNAL OF NEUROCHEMISTRY, 74( 5), 2167- 2173, May. 2000,  
19
Decrease in thromboxane A(2) receptor expression by differentiation with dibutyryl cyclic AMP in 1321N1 human astrocytoma cells , PROSTAGLANDINS & OTHER LIPID MEDIATORS, 58( 1), 51- 62, Aug. 1999,  
20
Human astrocytoma cells express two thromboxane A(2) receptor subtypes that communicate with G(q) and G(12) , PROSTAGLANDINS & OTHER LIPID MEDIATORS, 55( 2-3), 159- 168, Feb. 1998,  
21
Thromboxane A2 receptor-mediated signal transduction in glial cells. , Folia Pharmacologica Japonica, 112,  113- 117, 1998, https://doi.org/10.1254/fpj.112.supplement_113 

 

MISC
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date 
1
Effect of brefelamide on NGF-induced cell proliferation in 1321N1 human astrocytoma cells , JOURNAL OF PHARMACOLOGICAL SCIENCES, 130( 3), S228- S228, Mar. 2016 
2
Effect of HMG-CoA reductase inhibitors on mouse renal interstitial fibrosis , JOURNAL OF PHARMACOLOGICAL SCIENCES, 130( 3), S247- S247, Mar. 2016 
3
Effect of unilateral ureteral obstruction on compensatory renal hypertrophy in mice , JOURNAL OF PHARMACOLOGICAL SCIENCES, 128( 3), S203- S203, Jul. 2015 
4
Effect of brefelamide on GDNF-induced cell proliferation in 1321N1 human astrocytoma cells , JOURNAL OF PHARMACOLOGICAL SCIENCES, 128( 3), S159- S159, Jul. 2015 
5
Effect of calcium channel blocker on mouse renal interstitial fibrosis , JOURNAL OF PHARMACOLOGICAL SCIENCES, 124,  225P- 225P, 2014 
6
Effect of brefelamide on HGF-induced cell survival in 1321N1 human astrocytoma cells , JOURNAL OF PHARMACOLOGICAL SCIENCES, 124,  146P- 146P, 2014 
7
Interleukin-6 contributes to modulation of oxidative stress and apoptosis caused by cisplatin , JOURNAL OF PHARMACOLOGICAL SCIENCES, 124,  89P- 89P, 2014 
8
Effect of cyclooxygenase (COX)-2 selective inhibitor on mouse renal interstitial fibrosis , JOURNAL OF PHARMACOLOGICAL SCIENCES, 121,  167P- 167P, 2013 
9
Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor , JOURNAL OF PHARMACOLOGICAL SCIENCES, 118,  161P- 161P, 2012 
10
Participation of TrkA signaling on anti-proliferative activity of brefelamide in 1321N1 human astrocytoma cells , JOURNAL OF PHARMACOLOGICAL SCIENCES, 118,  183P- 183P, 2012 
11
Dimethylthiourea improves cisplatin-induced acute renal failure via upregulation of interleukin-6 and anti-apoptotic factors , JOURNAL OF PHARMACOLOGICAL SCIENCES, 115,  161P- 161P, 2011 
12
Acute renal failure is accelerated through a phosphorylation of ERK and oxidative stress in interleukin-6 knockout mice treated with cisplatin , JOURNAL OF PHARMACOLOGICAL SCIENCES, 112,  153P- 153P, 2010 
13
Brefelamide inhibits phosphorylation of ERK through a reduction of epidermal growth factor receptor in human astrocytoma cells , JOURNAL OF PHARMACOLOGICAL SCIENCES, 106,  186P- 186P, 2008 
14
Thromboxane A(2) receptor-mediated G(12/13)-dependent glial morphological change. , JOURNAL OF PHARMACOLOGICAL SCIENCES, 103,  188P- 188P, 2007 
15
Morphological change of human astrocytoma cells by thromboxane A(2) receptor stimulation. , JOURNAL OF PHARMACOLOGICAL SCIENCES, 91,  80P- 80P, 2003 

 

Research Grants & Projects
No.Offer organization, System name, Title, Fund classification, Date 
1
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Pathophysiological role of renin-angiotensin system and Rho in renal failure, ,  2007 - 2008 
2
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, The new pathophysiological role and its mechanism of angiotensin receptor, ,  2005 - 2006 
3
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Research for the molecular mechanism regulating multu-functresponses mediated via G protein-coupled receptors, ,  2002 - 2003