Takasaki University of Health and Welfare

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Takasaki University of Health and Welfare top

IMAI Jun

Profile Research field Research achievement Educational achievement Management achievement Social contribution achievement

 

Books etc
No.Title URL, Autour Type, Publisher, Publication date, Range, ISBN 
1
日本発ブロックバスターを目指して , , , 2010, ,  

 

Published Papers
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI 
1
Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice , Antioxidants, 19( 9),  , 2021,  
2
Detection of benefificial anti-allergy microbes by dendritic cells , , 40( 10), 61- 66, 2020,  
3
Dendritic cells as a detecting unit for beneficial anti-allergy microbers. , The Allergy in Practice, 40( 6), 50- 54, 2020,  
4
Endoplasmic Reticulum-Associated Degradation-Dependent Processing in Cross-Presentation and Its Potential for Dendritic Cell Vaccinations. Pharmaceutics. , Pharmaceutics, 13( 12), pii: E153- , 2020,  
5
Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation. Imai J, Otani M, Sakai T. , , 20( 22),  , Nov. 2019,  
6
An optical and non-invasive method to detect the accumulation of ubiquitin chains. , , ,   , Mar. 2019,  
7
Cytoplasmic OH scavenger TA293 attenuates cellular senescence and fibrosis by activating macrophages through oxidized phospholipids/TLR4. , , 221,  284- 292, Mar. 2019,  
8
Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence. , International J Molecular Science, 20( 2), pii: E456.- , Jan. 2019,  
9
Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation , JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 21( 126), doi: 10.3791/55949- , Aug. 2017, https://doi.org/10.3791/55949 
10
The novel antioxidant TA293 reveals the role of cytoplasmic hydroxyl radicals in oxidative stress-induced senescence and inflammation , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 482( 4), 1183- 1189, Jan. 2017, https://doi.org/10.1016/j.bbrc.2016.12.009 
11
The specialized subcellular compartments for endoplasmic reticulum-associated degradation of exogenous antigens in DCs. , Cellular Immunology & Immunotherapeutics, 2( 1), 1- 7, 2017,  
12
Development of a novel cytoplasmic hydroxyl radical-targeting antioxidant (TA293) that suppresses cellular senescence, inflammation, and apoptosis. , Inflamm Cell Signal, 4,  e1539- , 2017,  
13
Non Classical Endosomal Compartments Play Important Roles in Cross-Presentation by Dendritic Cells. , Open Access Journal of Pharmaceutical Research, 1,  000121- , 2017,  
14
Purification of the subcellular compartment in which exogenous antigens undergo endoplasmic reticulum-associated degradation from dendritic cells , Heliyon, 2( 9), e00151- , Sep. 1, 2016, https://doi.org/10.1016/j.heliyon.2016.e00151 
15
The subcellular compartment for endoplasmic reticulum- associated degradation of exogenous antigens from dendritic cells. , Science Proceedings, 3,  e1490- , 2016,  
16
The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function , INTERNATIONAL IMMUNOLOGY, 20( 10), 1259- 1268, Oct. 2008, https://doi.org/10.1093/intimm/dxn082 
17
Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells. , International Immunology, 17( 1), 45- 53, Nov. 2004,  
18
The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome. , EMBO Journal, 22( 14), 3557- 3567, May. 2003,  
19
Proteasomes and Molecular Chaperones Cellular Machinery Responsible for Folding and Destruction of Unfolded Proteins , CELL CYCLE, 2( 6), 585- 589, 2003, https://doi.org/10.4161/cc.2.6.586 
20
Interaction between the N-terminal and middle regions is essential for the in vivo function of HSP90 molecular chaperone , JOURNAL OF BIOLOGICAL CHEMISTRY, 277( 38), 34959- 34966, Sep. 2002, https://doi.org/10.1074/jbc.M203038200 
21
The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast. , Journal of Cell Science,, 115( 23), 4629- 4639, Aug. 2002,  
22
Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin , Molecular and Cellular Biology, 20( 24), 9262- 9270, 2000, https://doi.org/10.1128/MCB.20.24.9262-9270.2000 
23
Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70 , MOLECULAR AND CELLULAR BIOLOGY, 19( 5), 3580- 3587, May. 1999,  
24
Genetic analysis of the Saccharomyces cerevisiae RHO3 gene, encoding a rho-type small GTPase, provides evidence for a role in bud formation. , , 142( 2), 359- 369, Jan. 1996,  
25
A GENETIC SYSTEM CONTROLLING MITOCHONDRIAL FUSION IN THE SLIME-MOLD, PHYSARUM-POLYCEPHALUM , GENETICS, 133( 2), 213- 224, Feb. 1993,  

 

MISC
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date 
1
学校薬剤師の活動を想定した環境衛生実習 , 日本薬学会年会要旨集(CD-ROM), 135th,  ROMBUNNO.26PB-AM274- , 2015 
2
Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells , CELL STRUCTURE AND FUNCTION, 30,  18- 18, Jun. 2005 

 

Conference Activities & Talks
No.Title, Conference, Publication date, Promoter, Venue 
1
The molecular chaperone, Hsp90, interacts with the proteasomes and essential for their assemblies., Cold Spring Harbor meeting on Molecular Chaperone & The Heat Shock Response., Apr. 2002, ,  

 

Industrial Property Rights
No.Type, Title, ApplicationId, ApplicationDate, PatentId, Registration date, PatentDate 
1
patent_right, METHODS FOR SELECTING CANDIDATE PEPTIDES PRESENTED ON THE SURFACE OF CANCER CELLS FOLLOWING THEIR BINDONG TO MHC CLASS I MOLECULES, 特願12/313,855, Nov. 25, 2008, ,  ,   
2
patent_right, METHODS FOR PRODUCING DENDRITIC CELLS THAT HAVE ACQUIRED CTL-INDUCING ABILITY, 特願11/574,641, Sep. 2, 2005, ,  ,   
3
patent_right, METHODS FOR PRODUCING DENDRITIC CELLS THAT HAVE ACQUIRED CTL-INDUCING ABILITY, 特願05781377.6, Sep. 2, 2005, ,  ,   
4
patent_right, METHODS FOR PRODUCING DENDRITIC CELLS THAT HAVE ACQUIRED CTL-INDUCING ABILITY, 特願2006-532003, Sep. 2, 2005, ,  ,   
5
patent_right, METHODS FOR SELECTING PROTEINS THAT ARE READILY PRESENTED AS ANTIGENS ON DENDRITIC CELLS, 特願11/574,612, Sep. 2, 2005, ,  ,   
6
patent_right, METHODS FOR SELECTING PROTEINS THAT ARE READILY PRESENTED AS ANTIGENS ON DENDRITIC CELLS, 特願05781376.8, Sep. 2, 2005, ,  ,