Takasaki University of Health and Welfare

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SAKAI Takahiro

Profile Research field Research achievement Educational achievement Management achievement Social contribution achievement

 

Published Papers
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI 
1
Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice , Antioxidants, 9( 10), 1398- 1398, Aug. 2021, https://doi.org/10.3390/antiox10091398 
2
Detections of beneficial anti-allergy microbes by dendritic cells , , 40( 10), 829- 834, Sep. 2020,  
3
Dendritic cells as a detecting unit for beneficial anti-allergy microbes , , 40( 6), 13- 17, Jun. 2020,  
4
Endoplasmic Reticulum-Associated Degradation-Dependent Processing in Cross-Presentation and Its Potential for Dendritic Cell Vaccinations , Pharmaceutics, 12( 2),  , Feb. 2020,  
5
Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation. , , 20( 22),  , Nov. 2019,  
6
An optical and noninvasive method to detect the accumulation of ubiquitin chains , Cell Biology International, 43( 5),  , May. 2019, https://doi.org/10.1002/cbin.11186 
7
Cytoplasmic ・OH scavenger TA293 attenuates cellular senescence and fibrosis by activating macrophages through oxidized phospholipids/TLR4. , Life Sciences, 221( 15), 284- 292, Feb. 2019, https://doi.org/10.1016/j.lfs.2019.02.038 
8
Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence. , International Journal of Molecular Sciences, 20( 2),  , Jan. 2019, https://doi.org/10.3390/ijms20020456 
9
Research for effects of spring quality upon oxidative stress , , 39,  16- 21, Jun. 2018,  
10
Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation , Journal of Visualized Experiments, ( 126),  , Aug. 2017, https://doi.org/10.3791/55949 
11
Development of a novel cytoplasmic hydroxyl radical-targeting antioxidant (TA293) that suppresses cellular senescence, inflammation, and apoptosis , Inflammation and Cell Signaling, 4,  e1539- , Mar. 2017,  
12
The novel antioxidant TA293 reveals the role of cytoplasmic hydroxyl radicals in oxidative stress-induced senescence and inflammation , Biochemical and Biophysical Research Communications, 482( 4), 1183- 1189, Jan. 2017, https://doi.org/10.1016/j.bbrc.2016.12.009 
13
The specialized subcellular compartments for endoplasmic reticulum-associated degradation of exogenous antigens in DCs. , Cellular Immunology & Immunotherapeutics, 2( 1), 1- 7, 2017,  
14
Non Classical Endosomal Compartments Play Important Roles in Cross-Presentation by Dendritic Cells , Open Access Journal of Pharmaceutical Research, 1,  1 e000121- , 2017,  
15
Purification of the subcellular compartment in which exogenous antigens undergo endoplasmic reticulum-associated degradation from dendritic cells , Heliyon, 2( 9), e00151- , Sep. 1, 2016, https://doi.org/10.1016/j.heliyon.2016.e00151 
16
The subcellular compartment for endoplasmic reticulum- associated degradation of exogenous antigens from dendritic cells. , , 3( e1490),  , 2016,  
17
5-Stabilized Phosphatidylinositol 3,4,5-Trisphosphate Analogues Bind Grp1 PH, Inhibit Phosphoinositide Phosphatases, and Block Neutrophil Migration , CHEMBIOCHEM, 11( 3), 388- 395, Feb. 2010, https://doi.org/10.1002/cbic.200900545 
18
Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits , GENOME RESEARCH, 18( 3), 500- 508, Mar. 2008, https://doi.org/10.1101/gr.7175308 
19
The physiology of Phosphoinositides , BIOLOGICAL & PHARMACEUTICAL BULLETIN, 30( 9), 1599- 1604, Sep. 2007, https://doi.org/10.1248/bpb.30.1599 
20
Establishment of mouse inter-subspecific consomic strains for genetic dissection of complex traits , GENES & GENETIC SYSTEMS, 81( 6), 427- 427, Dec. 2006,  
21
Identification of a protanomalous chimpanzee by molecular genetic and electroretinogram analyses , VISION RESEARCH, 45( 10), 1225- 1235, May. 2005, https://doi.org/10.1016/j.visres.2004.11.016 
22
Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci , MAMMALIAN GENOME, 16( 1), 11- 19, Jan. 2005, https://doi.org/10.1007/s00344-004-3013-9 
23
Update of mouse microsatellite database of Japan (MMDBJ) , EXPERIMENTAL ANIMALS, 53( 2), 151- 154, Apr. 2004,  
24
Molecular phylogeny of Japanese Rhinolophidae based on variations in the complete sequence of the mitochondrial cytochrome b gene , GENES & GENETIC SYSTEMS, 78( 2), 179- 189, Apr. 2003,  

 

MISC
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date 
1
酸化ストレスを制御する泉質の探索 , 日本健康開発雑誌, ( 39), 16‐21- , Jun. 2018 
2
学校薬剤師の活動を想定した環境衛生実習 , 日本薬学会年会要旨集(CD-ROM), 135th,  ROMBUNNO.26PB-AM274- , 2015 
3
新規ミトコンドリア標的抗酸化剤の開発とモデルマウスを用いた薬理効果の検討 , 日本実験動物学会総会講演要旨集, 58th,  155- , May. 2011 
4
酸化的DNA損傷並びに放射線によって誘発される突然変異・発がんの分子機構 放射線誘発消化管腫瘍におけるApc遺伝子不活化の機構 , 日本放射線影響学会大会講演要旨集, 48回,  100- 100, Nov. 2005 
5
放射線誘発消化管腫瘍におけるApc遺伝子不活化の機構 , 日本放射線影響学会大会講演要旨集, 48th,  (JA)100,(EN)ABSTRACTS 106- , 2005 
6
Update of mouse microsatellite database of Japan (MMDBJ) , EXPERIMENTAL ANIMALS, 53( 2), 151- 154, Apr. 2004 
7
【ユニークな創薬ターゲット分子 夢の薬に向かって】 遺伝性疾患治療のための創薬ターゲット分子 遺伝性難聴の治療薬・診断薬のターゲット分子 , 医学のあゆみ, 207( 1), 83- 89, Oct. 2003 
8
mtDNAに基づく日本産Rhinolophoideaの分子系統学的研究 , 日本遺伝学会大会プログラム・予稿集, 73rd,  106- , Aug. 22, 2001 
9
マイクロサテライト多型解析に基づく実験用マウス系統の起源の探索 , 日本分子生物学会年会プログラム・講演要旨集, 23rd,  721- , Nov. 25, 2000 
10
伊豆大島におけるキクガシラコウモリRhinolophus ferrumequinumの分子系統学的研究 , 日本哺乳類学会大会プログラム・講演要旨集, 1999,  197- , Oct. 1, 1999