Takasaki University of Health and Welfare

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OKADA Yuko

Profile Research field Research achievement Educational achievement Management achievement Social contribution achievement

 

Published Papers
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI 
1
Effect of a Dietary Supplement Containing Raspberry Ketone on CYP3A Activity in Healthy Women , Pharmaceutica Analytica Acta, 09( 06),  , 2018, https://doi.org/10.4172/2153-2435.1000587 
2
Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3 , BIOCHEMICAL GENETICS, 55( 3), 268- 277, Jun. 2017, https://doi.org/10.1007/s10528-017-9795-8 
3
Analysis of cytochrome P450 gene polymorphism in a lupus nephritis patient in whom tacrolimus blood concentration was markedly elevated after administration of azole antifungal agents , JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 38( 1), 74- 76, Feb. 2013, https://doi.org/10.1111/jcpt.12004 
4
Effect of genetic polymorphisms on effectiveness of low-dose azathioprine in Japanese patients with systemic lupus erythematosus , AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 69( 23), 2072- 2078, Dec. 2012, https://doi.org/10.2146/ajhp120179 
5
CYP4F2 gene polymorphism as a contributor to warfarin maintenance dose in Japanese subjects , JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 37( 4), 481- 485, Aug. 2012, https://doi.org/10.1111/j.1365-2710.2011.01317.x 
6
Pharmacokinetics Parameters in Drug Package Inserts (3) , Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 37( 9), 543- 550, 2011, https://doi.org/10.5649/jjphcs.37.543 
7
Pharmacokinetic Individualization of High-Dose Methotrexate Chemotherapy for the Treatment of Localized Osteosarcoma , JOURNAL OF CHEMOTHERAPY, 22( 3), 186- 190, Jun. 2010, https://doi.org/10.1179/joc.2010.22.3.186 
8
Inosine triphosphate pyrophosphatase 94C > A polymorphism: clinical implications for patients with systemic lupus erythematosus treated with azathioprine , EXPERT OPINION ON DRUG SAFETY, 9( 3), 447- 457, May. 2010, https://doi.org/10.1517/14740330903544474 
9
Pro32Thr Polymorphism of Inosine Triphosphate Pyrophosphatase Gene Predicts Efficacy of Low-Dose Azathioprine for Patients With Systemic Lupus Erythematosus , CLINICAL PHARMACOLOGY & THERAPEUTICS, 85( 5), 527- 530, May. 2009, https://doi.org/10.1038/clpt.2008.261 
10
Development of a single-tube PCR-pyrosequencing method for the simultaneous and rapid detection of four variant alleles of CYP2C9 gene polymorphism , JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 33( 2), 187- 192, Apr. 2008, https://doi.org/10.1111/j.1365-2710.2007.00895.x 
11
Thiopurine methyltransferase genotype and phenotype status in Japanese patients with systemic lupus erythematosus , BIOLOGICAL & PHARMACEUTICAL BULLETIN, 28( 11), 2117- 2119, Nov. 2005, https://doi.org/10.1248/bpb.28.2117 
12
Time-dependent induction of midazolam-1-hydroxylation enzymes in rats treated with St. John's wort , BIOLOGICAL & PHARMACEUTICAL BULLETIN, 28( 8), 1467- 1471, Aug. 2005, https://doi.org/10.1248/bpb.28.1467 
13
Genetic polymorphism of CYP2C9 and CYP2C19 in a Bolivian population: an investigative and comparative study , EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 61( 3), 179- 184, May. 2005, https://doi.org/10.1007/s00228-004-0890-5 
14
Genotyping of thiopurine methyltransferase using pyrosequencing(TM) , BIOLOGICAL & PHARMACEUTICAL BULLETIN, 28( 4), 677- 681, Apr. 2005, https://doi.org/10.1248/bpb.28.677 
15
Effect of the single CYP2C9*3 allele on pharmacokinetics and pharmacodynamics of losartan in healthy Japanese subjects , EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 59( 8-9), 589- 592, Nov. 2003, https://doi.org/10.1007/s00228-003-0664-5 
16
Fluvoxamine modulates pain sensation and affective processing of pain in human brain , NEUROREPORT, 14( 6), 791- 797, May. 2003, https://doi.org/10.1097/01.wnr.0000069965.11849.28 
17
Successful treatment of severe hyperammonemia using sodium phenylacetate powder prepared in hospital pharmacy , BIOLOGICAL & PHARMACEUTICAL BULLETIN, 25( 9), 1244- 1246, Sep. 2002, https://doi.org/10.1248/bpb.25.1244 
18
High catalytic activity of human cytochrome P450 co-expressed with human NADPH-cytochrome P450 reductase in Escherichia coli , BIOCHEMICAL PHARMACOLOGY, 55( 8), 1315- 1325, Apr. 1998, https://doi.org/10.1016/S0006-2952(97)00643-6 

 

MISC
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date 
1
Comparison of standardized instructions and pharmaceutical companies’ instructions in learning inhalation skills by pharmacy students: Randomized controlled trial , 日本薬学会年会要旨集(CD-ROM), 140th (Web),   , 2020 
2
レセプトデータを用いた妊娠中の抗うつ薬が出生児出生児への影響の解析 , 日本薬学会年会要旨集, 137年会( 4), 155- 155, Mar. 2017 
3
レセプトデータを用いた妊娠高血圧の実態と治療薬の出生児への影響の解析 , 日本薬学会年会要旨集, 137年会( 4), 155- 155, Mar. 2017 
4
薬学生による高校生対象の喫煙防止教室の構築 , 日本ファーマシューティカルコミュニケーション学会会誌, 14( 2), 6- 12, Oct. 2016 
5
薬学実務実習生アンケートにみる在宅医療実習の現状と今後への取り組み , 日本薬学会年会要旨集, 136年会( 4), 227- 227, Mar. 2016 
6
高校生を対象とした効果的な喫煙防止教室実施のための生活環境調査 , 日本薬学会年会要旨集, 135年会( 3), 247- 247, Mar. 2015 
7
抗精神病薬の処方実態と適切な薬物治療を行うための薬剤師の役割についての検討 , 日本薬学会年会要旨集, 135年会( 4), 181- 181, Mar. 2015 
8
高校生を対象とした薬学生による喫煙防止教室の効果についての検討 , 日本薬学会年会要旨集, 135年会( 3), 247- 247, Mar. 2015 
9
高校生を対象とした薬学生による効果的な喫煙防止教室の構築 , 日本薬学会年会要旨集, 135年会( 3), 248- 248, Mar. 2015 
10
Effect of a dietary supplement containing raspberry ketone on cytochrome P450 3A activity , Pharmaceutica Analytica Acta, 5( 6), 302- , 2014 
11
医薬品添付文書中の薬物動態パラメータの研究 ジェネリック医薬品の生物学的同等性試験における薬物動態パラメータの試験間および試験内変動の解析 , 医療薬学, 37( 9), 543- 550, Sep. 2011 
12
SLE患者に対するAZAの治療効果におけるAZA代謝酵素の遺伝子多型が与える影響 , 日本薬学会年会要旨集, 131年会( 3), 169- 169, Mar. 2011 
13
Individualization of azathioprine dose for patients with systemic lupus erythematosus , PHARMACY WORLD & SCIENCE, 32( 2), 308- 309, Apr. 2010 
14
「薬が効かない」を科学する アザチオプリンの治療効果に対するITPA 94C>A遺伝子多型の影響 , 医薬ジャーナル, 45( 12), 3089- 3094, Dec. 2009 
15
Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in patients with rheumatoid arthritis and lupus nephritis. , Drug Metab. Rev., 41( Suppl 2), 108- , 2009 
16
アザチオプリンの治療効果に対するITPA 94C>A遺伝子型の影響 , 臨床薬理, 38( Suppl.), S182- S182, Nov. 2007 
17
日本人におけるワルファリン抵抗性の原因となる遺伝子多型解析 , 臨床薬理の進歩, ( 27), 89- 94, Jul. 2006 
18
ラズベリーケトン製剤がCYP3A酵素活性に及ぼす影響の検討 , 臨床薬理, 35( Suppl.), S177- S177, Aug. 2004 
19
SLEに対するシクロフォスファミド・パルス療法の臨床効果とCYP遺伝子多型に関する検討 , 日本薬学会年会要旨集, 124年会( 4), 26- 26, Mar. 2004 
20
SLEに対するシクロフォスファミドのパルス療法の臨床効果とCYP2B6,CYP2C9,CYP2C19遺伝子多型に関する検討 , 日本薬学会年会要旨集, 123年会( 4), 41- 41, Mar. 2003 
21
CYP2C9遺伝的多型がLosartanの体内動態及び血圧降下作用に及ぼす影響 , 臨床薬理, 34( 1), 29S- 30S, Jan. 2003 
22
Paroxetineの併用により血中theophylline濃度が上昇した1症例 , 日本神経精神薬理学雑誌, 22( 6), 309- 309, Dec. 2002 
23
Case report summary browsing system for education of pharmaceutical students through the Internet , Yakugaku Zasshi, 122( 6), 381- 388, Jun. 2002 

 

Awards & Honors
No.Publication date, Association, Prize, Subtitle 
1
Dec. 2010, The Japanese Society of Clinical Pharmacology and Therapeutics, Research Award for Japan Research Foundation for Clinical Pharmacology, Pro32Thr Polymorphism of Inosine Triphosphate Pyrophosphatase Gene Predicts Efficacy of Low-dose Azathioprine for Patients with Systemic Lupus Erythematosus