Takasaki University of Health and Welfare

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KUWABARA Atsushi

Profile Research field Research achievement Educational achievement Management achievement Social contribution achievement

 

Published Papers
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI 
1
Lipoprotein-associated lysolipids are differentially involved in high-density lipoprotein- and its oxidized form-induced neurite remodeling in PC12 cells , NEUROCHEMISTRY INTERNATIONAL, 68,  38- 47, Mar. 2014, https://doi.org/10.1016/j.neuint.2014.02.005 
2
Mechanism and Role of High Density Lipoprotein-induced Activation of AMP-activated Protein Kinase in Endothelial Cells , JOURNAL OF BIOLOGICAL CHEMISTRY, 285( 7), 4387- 4397, Feb. 2010, https://doi.org/10.1074/jbc.M109.043869 
3
LPA(1) receptors mediate stimulation, whereas LPA(2) receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites , CARCINOGENESIS, 30( 3), 457- 465, Mar. 2009, https://doi.org/10.1093/carcin/bgp011 
4
HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 359( 3), 649- 654, Aug. 2007, https://doi.org/10.1016/j.bbrc.2007.05.131 
5
Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells , AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 292( 5), H2513- H2522, May. 2007, https://doi.org/10.1152/ajpheart.00865.2006 
6
Role of scavenger receptor class B type I and sphingosine 1-phosphate receptors in high density lipoprotein-induced inhibition of adhesion molecule expression in endothelial cells , JOURNAL OF BIOLOGICAL CHEMISTRY, 281( 49), 37457- 37467, Dec. 2006, https://doi.org/10.1074/jbc.M605823200 

 

MISC
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date 
1
Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells.(共著) , Biochem J., 353( 1), 139- 146, 2001 
2
Sphingosine 1-phosphate stimulates insulin secretion in HIT-T 15 cells and mouse islets , Endocrine Journal, 47( 3), 261- 269, 2000 
3
Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions.(共著) , Biochem J., 352( 3), 809- 815, 2000 
4
Circulating interleukin-6 significantly correlates to thyroid hormone in acute myocardial infarction but not in chronic heart failure.(共著) , J Endocrinol Invest., 23( 8), 509- 514, 2000 
5
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3.(共著) , Biochem J., 348( 1), 71- 76, 2000 
6
Involvement of circulating interleukin-6 and its receptor in the development of euthyroid sick syndrome in patients with acute myocardial infarction.(共著) , Eur J Endocrinol., 143( 2), 179- 184, 2000 
7
Type IV collagen as an early marker for diabetic nephropathy in non-insulin-dependent diabetes mellitus.(共著) , J Diabetes Complications., 14( 1),  , 2000 
8
Comparison of intrinsic activities of the putative sphingosine 1-phosphate receptor subtypes to regulate several signaling pathways in their cDNA-transfected Chinese hamster ovary cells.(共著) , J Biol Chem., 274( 34), 23940- 23947, 1999 
9
Activation of phospholipase C-Ca2+ system by sphingosine 1-phosphate in CHO cells transfected with Edg-3, a putative lipid receptor.(共著) , FEBS Lett., 443( 1), 25- 30, 1999 
10
Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells.(共著) , Biochem J., 336( Pt2), 491- 500, 1998 
11
Participation of the pituitary-thyroid axis in the cardiovascular system in elderly patients with congestive heart failure.(共著) , J Med., 28( 1-2), 75- 80, 1997 
12
Inhibition of TSH-induced hydrogen peroxide production by TNF-alpha through a sphingomyelinase signaling pathway.(共著) , Am J Physiol., 273( 3Pt1), E639-E643- , 1997 
13
Untreated Graves' but not remission Graves' immunoglobulin G preparations increase intracellular Ca2+ in FRTL-5 thyroid cells.(共著) , Endocr J., 43( 5), 457- 467, 1996 
14
Both cyclooxygenase and lipoxygenase inhibitor partially restore the anorexia by interleukin-1 beta.(共著) , Life Sci., 51( 18), 1419- 1426, 1992 
15
Enhanced sensitivity to anorexia and consumption of drinking water induced by interleukin-1 beta in obese yellow mice.(共著) , Eur J Pharmacol., 209( (1-2)), 15- 18, 1991 
16
Contemplation of age-adjusted standard values of lipid profiles in Japan.(共著) , J Med 2001 in press, ,   ,   

 

Research Grants & Projects
No.Offer organization, System name, Title, Fund classification, Date 
1
, , Distribusin of sphingosine 1-phosphate in the blood., competitive_research_funding,