| Published Papers |
| No. | Ｔitle URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI
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| 1 |
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| 2 |
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| 3 | Constitutive androstane receptor-responsive elements for mouse Cyp1a2 transcriptional activation induced by constitutive androstane receptor ligands , Drug Metabolism and Pharmacokinetics, 48, 100485- 100485, Feb. 2023, https://doi.org/10.1016/j.dmpk.2022.100485 |
| 4 | Androgen receptor phosphorylated at Ser815: The expression and function in the prostate and tumor-derived cells. , Biochemical pharmacology, 194, 114794- 114794, Dec. 2021, https://doi.org/10.1016/j.bcp.2021.114794 |
| 5 | Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation. , Biochemical and biophysical research communications, 514( 2), 456- 461, Jun. 2019, https://doi.org/10.1016/j.bbrc.2019.04.125 |
| 6 | Mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways , Oncology Letters, 15( 2), 1758- 1762, Feb. 1, 2018, https://doi.org/10.3892/ol.2017.7532 |
| 7 | Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain , SCIENTIFIC REPORTS, 6, 31502- , Aug. 2016, https://doi.org/10.1038/srep31502 |
| 8 |
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| 9 | Inverse correlation between Thr-669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation , Cancer Science, 104( 10), 1315- 1322, Oct. 2013, https://doi.org/10.1111/cas.12225 |
| 10 | Modified expression of aryl hydrocarbon receptor-related genes by deoxymiroestrol, a phytoestrogen, in mouse hepatocytes in primary culture , JOURNAL OF ETHNOPHARMACOLOGY, 137( 1), 902- 908, Sep. 2011, https://doi.org/10.1016/j.jep.2011.06.047 |
| 11 | Hepatocyte Nuclear Factor 4 alpha Regulates Expression of the Mouse Female-Specific Cyp3a41 Gene in the Liver , DRUG METABOLISM AND DISPOSITION, 39( 3), 490- 497, Mar. 2011, https://doi.org/10.1124/dmd.110.035980 |
| 12 | Regulatory Xenobiotic Responsive Elements in the Distal 5'-Flanking Region of the Mouse Cyp1a2 Gene Required for Transcriptional Activation by 3-Methylcholanthrene and 2,3,7,8-Tetrachlorodibenzo-p-dioxin , DRUG METABOLISM AND DISPOSITION, 38( 10), 1640- 1643, Oct. 2010, https://doi.org/10.1124/dmd.109.031856 |
| 13 |
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| 14 | Gender-associated modulation of inducible CYP1A1 expression by andrographolide in mouse liver , EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 39( 5), 394- 401, Mar. 2010, https://doi.org/10.1016/j.ejps.2010.01.009 |
| 15 | Alteration of Acetaminophen-induced Cytotoxicity in Mouse Hepatocytes during Primary Culture , JOURNAL OF HEALTH SCIENCE, 55( 5), 767- 776, Oct. 2009, https://doi.org/10.1248/jhs.55.767 |
| 16 | Sex Differences of Drug-metabolizing Enzyme: Female Predominant Expression of Human and Mouse Cytochrome P450 3A Isoforms , JOURNAL OF HEALTH SCIENCE, 55( 3), 325- 337, Jun. 2009, https://doi.org/10.1248/jhs.55.325 |
| 17 | Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes , TOXICOLOGY AND APPLIED PHARMACOLOGY, 224( 2), 156- 162, Oct. 2007, https://doi.org/10.1016/j.taap.2007.07.008 |
| 18 | Pathogenic monoclonal antibody against desmoglein 3 augments desmoglein 3 and p38 MAPK phosphorylation in human squamous carcinoma cell line , AUTOIMMUNITY, 39( 7), 587- 590, Nov. 2006, https://doi.org/10.1080/08916930600971943 |
| 19 | Functional characterization of human organic cation transporter OCTN1 single nucleotide polymorphisms in the Japanese population , JOURNAL OF PHARMACEUTICAL SCIENCES, 93( 12), 2920- 2926, Dec. 2004, https://doi.org/10.1002/jps.20190 |
| 20 | Phosphatidylserine binding of class B scavenger receptor type I, a phagocytosis receptor of testicular Sertoli cells , JOURNAL OF BIOLOGICAL CHEMISTRY, 277( 30), 27559- 27566, Jul. 2002, https://doi.org/10.1074/jbc.M202879200 |
| 21 | Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells  , JOURNAL OF BIOLOGICAL CHEMISTRY, 274( 9), 5901- 5908, Feb. 1999, https://doi.org/10.1074/jbc.274.9.5901 |
| MISC |
| No. | Ｔitle URL, Journal, Vol( No), Start Page- End Page, Publication date
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| 1 | チロシンキナーゼ非依存的なリン酸化によるErbB4のフィードバック阻害機構 , 日本癌学会総会記事, 76回, P- 2066, Sep. 2017
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| 2 | チロシンキナーゼ非依存的なErbB4リン酸化の役割 , 日本癌学会総会記事, 75回, P- 1180, Oct. 2016
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| 3 | 乳がん細胞におけるErbB2 Thr-677リン酸化によるErb2/ErbB3ヘテロダイマーのフィードバック阻害機構 , 日本癌学会総会記事, 74回, P- 2120, Oct. 2015
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| 4 | 炎症シグナルを介したEphA2のリン酸化制御(Molecular mechanism of phosphorylation of EphA2 induced by inflammatory signal) , 日本癌学会総会記事, 72回, 263- 263, Oct. 2013
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| 5 | リガンド濃度に依存したEGF受容体の多次元的リン酸化制御(Ligand concentration-dependent multidimentional phosphorylation of EGFR) , 日本癌学会総会記事, 71回, 72- 72, Aug. 2012
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| 6 | グルココルチコイドによるCyp3a41遺伝子の発現調節機構 Glucocorticoid receptorおよびHepatocyte nuclear factor 4αの役割 , 日本薬学会年会要旨集, 129年会( 3), 190- 190, Mar. 2009
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| 7 | Different anti-desmoglein 3 monoclonal antibodies exert epitope-specific regulation of p120-catenin phosphorylation and of p120-catenin binding to desmoglein 3 in human squamous cell line, DJM-1 cell , Journal of Investigative Dermatology, 126, 6- 6, Apr. 2006
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| Conference Activities & Talks |
| No. | Ｔitle, Conference, Publication date, Promoter, Venue
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| 1 | ERK-mediated feedback regulation of ErbB family via the conserved Thr phosphorylation, , Sep. 2018, ,
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| 2 | Feedback regulation of ErbB family via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain, The Second International Symposium on Toyama-Asia-Africa Pharmaceutical Network, Sep. 2017, ,
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| 3 | Down-regulation of ErbB2/ErbB3 heterodimer via ERK-mediated phosphorylation of ErbB2 Thr-677 in the juxtamembrane domain, The 12th International Conference on Protein Phosphatase, Oct. 2016, ,
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| 4 | 乳がん細胞におけるErbB2/ErbB3ヘテロ二量体のフィードバック阻害機構, , Oct. 2014, ,
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| 5 | 抗デスモグレイン(Dsg)3モノクローナル抗体によるDsg3結合型p120-cateninのリン酸化と結合性の検討, , Jun. 2006, ,
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| 6 | Different anti-desmoglein 3 monoclonal antibodies exert epitope-specific regulation of p120-catenin phosphorylation and of p120-catenin binding to desmoglein 3 in human squamous cell line, DJM-1 cell, The 67th Annual Meeting of the Society for Investigative Dermatology, May. 2006, ,
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| 7 | 精巣セルトリ細胞貪食受容体SR-BIのホスファチジルセリンへの結合, , Aug. 2002, ,
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| Research Grants & Projects |
| No. | Offer organization, System name, Title, Fund classification, Date
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| 1 | Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Noncanonical activation of receptor tyrosine kinases: next target mechanisms for cancer progression, , Apr. 2016 - Mar. 2019
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| 2 | Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Role of epigenetic regulation on female-predominant expression of drug-metabolizing enzyme CYP3A gene, , Apr. 2011 - Mar. 2015
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| 3 | Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Molecular mechanism of CYP1A2 gene expression in male regulated bygrowth hormone for personalized medicine, competitive_research_funding, 2011 - 2012
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| 4 | Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Mechanisms of female-specific expression of drug-metabolizing enzyme CYP3A : comparison between human and mouse, , 2008 - 2010
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| 5 | Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Sex-dependent expression mechanism of cytochrome P450 by growth hormone and a transcription factor, HNF3β or HNF4α, , 2007 - 2008
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