Published Papers |
No. | Title URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI
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4 | Biological Distribution after Oral Administration of Radioiodine-labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs and/or MRPs. , Pharmaceutics,, 15( 2), 497- , Feb. 2023, https://doi.org/10.3390/pharmaceutics15020497
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5 | A Single High-Dose Irradiation Changes Accumulation of Methotrexate and Gene Expression Levels of SLC and ABC Transporters in Cancer Cells , Frontiers in Pharmacology, 13, 1069321- 1069321, Jan. 2023, https://doi.org/10.3389/fphar.2022.1069321
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7 | Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1 , Drug Metabolism and Pharmacokinetics, , 100452- 100452, Feb. 2022, https://doi.org/10.1016/j.dmpk.2022.100452
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9 | MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells , Drug Metabolism and Disposition, 49( 9), 803- 809, Sep. 2021, https://doi.org/10.1124/dmd.121.000380
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13 | [131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma. , Nuclear medicine and biology, 90-91, 49- 54, Sep. 28, 2020, https://doi.org/10.1016/j.nucmedbio.2020.09.004
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14 | Toxicological implication of prostaglandin transporter SLCO2A1 inhibition by cigarette smoke in exacerbation of lung inflammation , Toxicology and Applied Pharmacology, , 115201- 115201, Aug. 2020, https://doi.org/10.1016/j.taap.2020.115201
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15 | Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction. , iScience, 23( 5), 101098- 101098, May. 22, 2020, https://doi.org/10.1016/j.isci.2020.101098
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16 | Transport mechanism and affinity of [99mTc]Tc-mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells , Nuclear Medicine and Biology, 84-85, 33- 37, May. 2020, https://doi.org/10.1016/j.nucmedbio.2020.01.002
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17 | The regulatory mechanism involved in the prostaglandin E2 disposition in carbon tetrachloride-induced liver injury. , Prostaglandins, leukotrienes, and essential fatty acids, 155, 102081- 102081, Apr. 2020, https://doi.org/10.1016/j.plefa.2020.102081
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18 | Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene. , Scientific reports, 10( 1), 4883- 4883, Mar. 17, 2020, 10.1038/s41598-020-61775-9
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19 | Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene. , Scientific reports, 10( 1), 4883- 4883, Mar. 17, 2020, https://doi.org/10.1038/s41598-020-61775-9
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20 | Identification of the Uptake Transporter Responsible for Distribution of Acotiamide into Stomach Tissue. , Molecular pharmaceutics, , , Mar. 10, 2020, 10.1021/acs.molpharmaceut.9b00894
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22 | The regulatory mechanism involved in the prostaglandin E2 disposition in carbon tetrachloride-induced liver injury. , Prostaglandins, leukotrienes, and essential fatty acids, 155, 102081- 102081, Feb. 21, 2020, 10.1016/j.plefa.2020.102081
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27 | Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia. , PLOS ONE, 14( 4), e0214862- , Apr. 2019, https://doi.org/10.1371/journal.pone.0214862
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28 | Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer. , Sci. Rep, 9( 1), 2245- , Feb. 2019,
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29 |
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31 | Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines. , Biopharmaceutics & drug disposition, 40( 1), 32- 43, Dec. 2018, https://doi.org/10.1002/bdd.2167
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32 | Different efflux transporter affinity and metabolism of 99mTc-2-methoxyisobutylisonitrile and 99mTc-tetrofosmin for multidrug resistance monitoring in cancer , Pharm Res, 36( 1), 18- 18, Nov. 2018, https://doi.org/10.1007/s11095-018-2548-5
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33 | Experimental evidence for re-secretion of PGE2 across rat alveolar epithelium by OATP2A1/SLCO2A1-mediated transcellular transport , J Pharmacol Exp Ther, 368( 2), 317- 325, Nov. 2018, https://doi.org/10.1124/jpet.118.249789
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34 |
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36 | INVOLVEMENT OF PROSTAGLANDIN TRANSPORTER IN MURINE PLACENTAL PGE(2) DEGRADATION , PLACENTA, 69, E86- , Sep. 2018,
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37 | Prostaglandin Transporter OATP2A1/SLCO2A1 Is Essential for Body Temperature Regulation during Fever. , The Journal of neuroscience : the official journal of the Society for Neuroscience, 38( 24), 5584- 5595, Jun. 13, 2018, https://doi.org/10.1523/JNEUROSCI.3276-17.2018
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38 | Contribution of equilibrative nucleoside transporters 1 and 2 to gemcitabine uptake in pancreatic cancer cells , Biopharmaceutics and Drug Disposition, 39( 5), 256- 264, May. 1, 2018, https://doi.org/10.1002/bdd.2131
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39 | Regulatory Effect of Fruit-derived Nanoparticle on Intestinal Transporters , FASEB JOURNAL, 32( 1), , Apr. 2018,
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40 | Impact of breast cancer resistance protein expression on the in vitro efficacy of anticancer drugs in pancreatic cancer cell lines , Drug Metabolism and Disposition, 46( 3), 214- 222, Mar. 1, 2018, https://doi.org/10.1124/dmd.117.078402
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41 | 細胞内PGE2シグナルにおけるOATP2A1の役割 , 細胞, 50, 151- 153, Mar. 2018,
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42 | Contribution of equilibrative nucleoside transporter(s) to intestinal basolateral and apical transports of anticancer trifluridine , Biopharmaceutics and Drug Disposition, 39( 1), 38- 46, Jan. 1, 2018, https://doi.org/10.1002/bdd.2110
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43 | Roles of Organic Anion Transporting Polypeptide 2A1 (OATP2A1/SLCO2A1) in Regulating the Pathophysiological Actions of Prostaglandins , AAPS Journal, 20( 1), 13- , Jan. 1, 2018, https://doi.org/10.1208/s12248-017-0163-8
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46 | プロスタグランジン輸送体が関わるPGE2分泌機構の提唱 , Bio Clinica, 32, 1117- 1121, Oct. 2017,
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48 | Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs , JOURNAL OF PHARMACEUTICAL SCIENCES, 106( 9), 2234- 2244, Sep. 2017, https://doi.org/10.1016/j.xphs.2017.04.011
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49 | Association of miR-145 With Statin-Induced Skeletal Muscle Toxicity in Human Rhabdomyosarcoma RD Cells , JOURNAL OF PHARMACEUTICAL SCIENCES, 106( 9), 2873- 2880, Sep. 2017, https://doi.org/10.1016/j.xphs.2017.04.005
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50 | Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban , JOURNAL OF PHARMACEUTICAL SCIENCES, 106( 9), 2524- 2534, Sep. 2017, https://doi.org/10.1016/j.xphs.2017.04.044
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51 |
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52 | Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions , DRUG METABOLISM AND DISPOSITION, 45( 2), 224- 227, Feb. 2017, https://doi.org/10.1124/dmd.116.072355
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53 | PHARMACOKINETIC EVALUATION OF DEHYDROEPIANDROSTERONE SULFATE (DHEAS) AS AN ENDOGENOUS PROBE TO PREDICT DRUG-DRUG INTERACTION ON HEPATIC OATP IN RATS , DRUG METABOLISM AND PHARMACOKINETICS, 32( 1), S52- S53, Jan. 2017, 10.1016/j.dmpk.2016.10.217
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54 | POTENTIAL OF PROSTAGLANDIN TRANSPORTER OATP2A1/SLCO2A1 AS A TARGET OF NOVEL ANTI-INFLAMMATORY DRUG , DRUG METABOLISM AND PHARMACOKINETICS, 32( 1), S102- S103, Jan. 2017, https://doi.org/10.1016/j.dmpk.2016.10.391
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55 |
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56 | PHARMACOKINETIC EVALUATION OF DEHYDROEPIANDROSTERONE SULFATE (DHEAS) AS AN ENDOGENOUS PROBE TO PREDICT DRUG-DRUG INTERACTION ON HEPATIC OATP IN RATS , DRUG METABOLISM AND PHARMACOKINETICS, 32( 1), S52- S53, Jan. 2017, https://doi.org/10.1016/j.dmpk.2016.10.217
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57 |
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58 | Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1 , JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 27( 111), 111- , May. 2016, https://doi.org/10.3791/53827
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59 | Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue , JOURNAL OF PHARMACEUTICAL SCIENCES, 105( 2), 925- 934, Feb. 2016, https://doi.org/10.1016/j.xphs.2015.11.036
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60 | Role of OATP2A1 in PGE(2) secretion from human colorectal cancer cells via exocytosis in response to oxidative stress , EXPERIMENTAL CELL RESEARCH, 341( 2), 123- 131, Feb. 2016, https://doi.org/10.1016/j.yexcr.2016.02.002
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61 | Analysis of the Metabolic Pathway of Bosentan and of the Cytotoxicity of Bosentan Metabolites Based on a Quantitative Modeling of Metabolism and Transport in Sandwich-Cultured Human Hepatocytes , DRUG METABOLISM AND DISPOSITION, 44( 1), 16- 27, Jan. 2016, https://doi.org/10.1124/dmd.115.067074
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62 |
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63 | Local Drug-Drug Interaction of Donepezil with Cilostazol at Breast Cancer Resistance Protein (ABCG2) Increases Drug Accumulation in Heart , DRUG METABOLISM AND DISPOSITION, 44( 1), 68- 74, Jan. 2016, https://doi.org/10.1124/dmd.115.066654
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64 | Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride , DRUG METABOLISM AND DISPOSITION, 44( 1), 1- 7, Jan. 2016, https://doi.org/10.1124/dmd.115.066712
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65 | Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug-drug interaction , MEDCHEMCOMM, 7( 9), 1775- 1782, 2016, https://doi.org/10.1039/c6md00235h
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66 |
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67 | OATP2A1/SLCO2A1-mediated prostaglandin E-2 loading into intracellular acidic compartments of macrophages contributes to exocytotic secretion , BIOCHEMICAL PHARMACOLOGY, 98( 4), 629- 638, Dec. 2015, https://doi.org/10.1016/j.bcp.2015.10.009
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68 | EFFECTS OF FRUIT JUICES ON INTESTINAL DRUG TRANSPORTER, PEPT1 , DRUG METABOLISM REVIEWS, 47, 282- , Nov. 20, 2015,
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69 | ARE UPTAKE TRANSPORTERS INVOLVED IN MEMBRANE TRANSPORT PROCESS OF ANTICOAGULANT DRUGS? , DRUG METABOLISM REVIEWS, 47, 295- , Nov. 20, 2015,
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70 | BIPHASIC HEPATIC UPTAKE OF GEMCITABINE CHARACTERIZED BY CONTRIBUTION OF ENT1 AND ENT2 , Drug Metabolism Reviews, 47, 246- 246, Nov. 20, 2015,
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71 | INCREASE OF RISK OF ACUTE RENAL FAILURE AND SERUM CREATININE LEVEL BY USE OF PIPERACILLIN/TAZOBACTAM , DRUG METABOLISM REVIEWS, 47, 181- , Nov. 20, 2015,
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72 | LOCALIZATION OF TRANSPORTER AND ENZYMES REGULATING PROSTAGLANDIN E-2 LEVEL IN MOUSE PLACENTA , DRUG METABOLISM REVIEWS, 47, 286- 287, Nov. 20, 2015,
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73 | UREMIC TOXINS ENHANCE BCRP-MEDIATED INTESTINAL URATE SECRETION IN CACO-2 CELLS , DRUG METABOLISM REVIEWS, 47, 289- 289, Nov. 20, 2015,
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74 | POSSIBLE INVOLVEMENT OF OATP2B1 IN GASTROINTESTINAL TOXICITY INDUCED BY SN-38, THE ACTIVE METABOLITE OF ANTICANCER IRINOTECAN , DRUG METABOLISM REVIEWS, 47, 287- 288, Nov. 2015,
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75 | PROSTAGLANDIN TRANSPORTER PGT RESPONSIBLE FOR REGULATING BIOLOGICAL FUNCTION OF EICOSAPENTAENOIC ACID-DERIVED PROSTAGLANDIN E-3 , DRUG METABOLISM REVIEWS, 47, 253- 253, Nov. 2015,
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76 | HEPATOCYTE-BASED MATHEMATICAL MODELING REVEALS A NOVEL METABOLIC PATHWAY OF BOSENTAN IN HUMAN LIVER , DRUG METABOLISM REVIEWS, 47, 202- 203, Nov. 2015,
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77 | RELEVANCE OF PROSTAGLANDIN TRANSPORTER (PGT) TO PGE(2) SECRETION FROM MACROPHAGES IN RESPONSE TO INFLAMMATORY STIMULATION , DRUG METABOLISM REVIEWS, 47, 288- 288, Nov. 2015,
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78 | PROSTAGLANDIN TRANSPORTER (PGT)-MEDIATED PGE2 SECRETION FROM HUMAN COLORECTAL CANCER CELLS IN RESPONSE TO OXIDATIVE STRESS , DRUG METABOLISM REVIEWS, 47, 296- 297, Nov. 2015,
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81 | Involvement of Concentrative Nucleoside Transporter 1 in Intestinal Absorption of Trifluridine Using Human Small Intestinal Epithelial Cells , JOURNAL OF PHARMACEUTICAL SCIENCES, 104( 9), 3146- 3153, Sep. 2015, https://doi.org/10.1002/jps.24455
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82 | Kinetic Evaluation of Determinant Factors for Cellular Accumulation of Protoporphyrin IX Induced by External 5-Aminolevulinic Acid for Photodynamic Cancer Therapy , JOURNAL OF PHARMACEUTICAL SCIENCES, 104( 9), 3092- 3100, Sep. 2015, https://doi.org/10.1002/jps.24462
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83 | Saturable Hepatic Extraction of Gemcitabine Involves Biphasic Uptake Mediated by Nucleoside Transporters Equilibrative Nucleoside Transporter 1 and 2 , JOURNAL OF PHARMACEUTICAL SCIENCES, 104( 9), 3162- 3169, Sep. 2015, https://doi.org/10.1002/jps.24498
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84 | Corrigendum to "Kinetic analyses of trans-1-amino-3-[<sup>18</sup>F]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2" [Nucl. Med. Biol, 2013, 40, 670-675], doi: 10.1016/j.nucmedbio.2013.03.009 , Nuclear Medicine and Biology, 42( 5), 513- 514, May. 1, 2015, https://doi.org/10.1016/j.nucmedbio.2014.12.013
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85 | Kinetic analyses of trans-1-amino-3-[F-18]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2 (vol 40, pg 670, 2013) , NUCLEAR MEDICINE AND BIOLOGY, 42( 5), 513- 514, May. 2015, https://doi.org/10.1016/j.nucmedbio.2014.12.013
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86 |
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87 | Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells , DRUG METABOLISM AND PHARMACOKINETICS, 30( 2), 133- 141, Apr. 2015, https://doi.org/10.1016/j.dmpk.2014.10.005
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88 | Modeling approach for multiple transporters-mediated drug-drug interactions in sandwich-cultured human hepatocytes: Effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide , DRUG METABOLISM AND PHARMACOKINETICS, 30( 2), 142- 148, Apr. 2015, https://doi.org/10.1016/j.dmpk.2014.10.006
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89 | Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells , BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 1849( 3), 317- 327, Mar. 2015, https://doi.org/10.1016/j.bbagrm.2015.01.003
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90 | In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells , JOURNAL OF PHARMACY AND PHARMACOLOGY, 67( 2), 170- 177, Feb. 2015, https://doi.org/10.1111/jphp.12328
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91 | Interaction of Drug or Food with Drug Transporters in Intestine and Liver , CURRENT DRUG METABOLISM, 16( 9), 753- 764, 2015,
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92 |
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93 | Accumulation of Trans-1-Amino-3-[F-18]Fluorocyclobutanecarboxylic Acid in Prostate Cancer due to Androgen-Induced Expression of Amino Acid Transporters , MOLECULAR IMAGING AND BIOLOGY, 16( 6), 756- 764, Dec. 2014, https://doi.org/10.1007/s11307-014-0756-x
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94 | Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers , BIOPHARMACEUTICS & DRUG DISPOSITION, 35( 8), 463- 484, Nov. 2014, https://doi.org/10.1002/bdd.1915
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95 | SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria , BIOPHARMACEUTICS & DRUG DISPOSITION, 35( 7), 391- 404, Oct. 2014, https://doi.org/10.1002/bdd.1909
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96 | Substrate- and Dose-Dependent Drug Interactions with Grapefruit Juice Caused by Multiple Binding Sites on OATP2B1 , PHARMACEUTICAL RESEARCH, 31( 8), 2035- 2043, Aug. 2014, https://doi.org/10.1007/s11095-014-1305-7
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97 |
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98 | Transport mechanisms of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with Tc-99m-N-pyridoxyl-5-methyltryptophan , NUCLEAR MEDICINE AND BIOLOGY, 41( 4), 338- 342, Apr. 2014, https://doi.org/10.1016/j.nucmedbio.2014.01.004
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99 | More Relevant Prediction for In Vivo Drug Interaction of Candesartan Cilexetil on Hepatic Bile Acid Transporter BSEP Using Sandwich-cultured Hepatocytes , DRUG METABOLISM AND PHARMACOKINETICS, 29( 1), 94- 96, Feb. 2014, https://doi.org/10.2133/dmpk.DMPK-13-NT-049
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100 | Mathematical Modeling of the in Vitro Hepatic Disposition of Mycophenolic Acid and Its Glucuronide in Sandwich-Cultured Human Hepatocytes , MOLECULAR PHARMACEUTICS, 11( 2), 568- 579, Feb. 2014, https://doi.org/10.1021/mp400513k
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101 | IMPACT OF OATP2B1 EXPRESSION ON CELL PROLIFERATION IN ER-POSITIVE BREAST CANCER , DRUG METABOLISM REVIEWS, 45, 268- 268, Jan. 2014,
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102 | MATHEMATICAL MODELING OF IN VITRO HEPATIC DISPOSITION OF MYCOPHENOLIC ACID AND ITS GLUCURONIDE IN SANDWICH-CULTURED HUMAN HEPATOCYTES , DRUG METABOLISM REVIEWS, 45, 163- 164, Jan. 2014,
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103 | LONG-LASTING INHIBITION OF INTESTINAL ABSORPTIVE TRANSPORTER OATP2B1 BY FRUIT JUICE , DRUG METABOLISM REVIEWS, 45, 120- 120, Jan. 2014,
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104 | Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1 , BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 1829( 12), 1288- 1299, Dec. 2013, https://doi.org/10.1016/j.bbagrm.2013.10.008
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105 | In Vivo Evidence of Organic Cation Transporter-Mediated Tracheal Accumulation of the Anticholinergic Agent Ipratropium in Mice , JOURNAL OF PHARMACEUTICAL SCIENCES, 102( 9), 3373- 3381, Sep. 2013, https://doi.org/10.1002/jps.23603
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106 | Kinetic analyses of trans-1-amino-3[F-18]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2 , NUCLEAR MEDICINE AND BIOLOGY, 40( 5), 670- 675, Jul. 2013, https://doi.org/10.1016/j.nucmedbio.2013.03.009
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107 | A role of prostaglandin transporter in regulating PGE(2) release from human bronchial epithelial BEAS-2B cells in response to LPS , JOURNAL OF ENDOCRINOLOGY, 217( 3), 265- 274, Jun. 2013, https://doi.org/10.1530/JOE-12-0339
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108 |
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109 | Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption , Drug Metabolism and Disposition, 41( 3), 615- 621, Mar. 2013, https://doi.org/10.1124/dmd.112.049635
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110 | Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate , NEPHROLOGY DIALYSIS TRANSPLANTATION, 28( 3), 603- 611, Mar. 2013, https://doi.org/10.1093/ndt/gfs574
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111 | Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions , JOURNAL OF PHARMACEUTICAL SCIENCES, 102( 1), 280- 288, Jan. 2013, https://doi.org/10.1002/jps.23357
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112 | Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions , Journal of Pharmaceutical Sciences, 102( 9), 3418- 3426, 2013, https://doi.org/10.1002/jps.23653
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113 |
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114 |
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115 | Enhanced expression of organic anion transporting polypeptides (OATPs) in androgen receptor-positive prostate cancer cells: Possible role of OATP1A2 in adaptive cell growth under androgen-depleted conditions , BIOCHEMICAL PHARMACOLOGY, 84( 8), 1070- 1077, Oct. 2012, https://doi.org/10.1016/j.bcp.2012.07.026
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116 | Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5 , BIOPHARMACEUTICS & DRUG DISPOSITION, 33( 6), 332- 341, Sep. 2012, https://doi.org/10.1002/bdd.1809
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117 | Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug-drug interaction induced by liver metabolites , TOXICOLOGY AND APPLIED PHARMACOLOGY, 263( 2), 244- 250, Sep. 2012, https://doi.org/10.1016/j.taap.2012.06.016
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118 | Species differences in the pharmacokinetics of KW-7158 [(2S)-(+)-3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide]: formation of hydrolyzed metabolite in human and animals , XENOBIOTICA, 42( 7), 649- 659, Jul. 2012, https://doi.org/10.3109/00498254.2011.652993
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119 |
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120 | Novel LC-MS/MS Method for Simultaneous Quantification of KW-7158, a New Drug Candidate for Urinary Incontinence and Bladder Hyperactivity, and its Metabolites in Rat Plasma: A Pharmacokinetic Study in Male and Female Rats , ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 62( 5), 213- 221, May. 2012, https://doi.org/10.1055/s-0032-1301883
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121 |
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122 | Genetic Polymorphisms of OATP Transporters and Their Impact on Intestinal Absorption and Hepatic Disposition of Drugs , DRUG METABOLISM AND PHARMACOKINETICS, 27( 1), 106- 121, Feb. 2012, https://doi.org/10.2133/dmpk.DMPK-11-RV-099
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123 | Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression , CHINESE JOURNAL OF CANCER, 31( 2), 73- 99, Feb. 2012, https://doi.org/10.5732/cjc.011.10320
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124 |
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125 |
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126 | Efflux transporter mRNA expression profiles in differentiating JEG-3 human choriocarcinoma cells as a placental transport model , Pharmazie, 67( 1), , 2012, https://doi.org/10.1691/ph.2012.1593
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127 | Functional Characterization of Apical Transporters Expressed in Rat Proximal Tubular Cells (PTCs) in Primary Culture , MOLECULAR PHARMACEUTICS, 8( 6), 2142- 2150, Nov. 2011, https://doi.org/10.1021/mp200096r
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128 | Solute Carrier Transporters as Targets for Drug Delivery and Pharmacological Intervention for Chemotherapy , JOURNAL OF PHARMACEUTICAL SCIENCES, 100( 9), 3731- 3750, Sep. 2011, https://doi.org/10.1002/jps.22576
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129 | Differential Effect of Grapefruit Juice on Intestinal Absorption of Statins Due to Inhibition of Organic Anion Transporting Polypeptide and/or P-glycoprotein , JOURNAL OF PHARMACEUTICAL SCIENCES, 100( 9), 3843- 3853, Sep. 2011, https://doi.org/10.1002/jps.22586
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130 | Oxaliplatin Transport Mediated by Organic Cation/Carnitine Transporters OCTN1 and OCTN2 in Overexpressing Human Embryonic Kidney 293 Cells and Rat Dorsal Root Ganglion Neurons , JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 338( 2), 537- 547, Aug. 2011, https://doi.org/10.1124/jpet.111.181297
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131 | Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine , BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 1809( 7), 295- 305, Jul. 2011, https://doi.org/10.1016/j.bbagrm.2011.06.004
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132 |
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133 | Quantitative Time-Lapse Imaging-Based Analysis of Drug-Drug Interaction Mediated by Hepatobiliary Transporter, Multidrug Resistance-Associated Protein 2, in Sandwich-Cultured Rat Hepatocytes , DRUG METABOLISM AND DISPOSITION, 39( 6), 984- 991, Jun. 2011, https://doi.org/10.1124/dmd.111.038059
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134 | Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats , BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1808( 6), 1441- 1447, Jun. 2011, https://doi.org/10.1016/j.bbamem.2010.11.002
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135 | Mechanism and interaction of absorptive drug transporters , DRUG METABOLISM REVIEWS, 43, 4- 5, May. 2011,
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136 | Upregulation of organic anion-transporting polypeptide (OATP) 1A2 by depletion of androgens; a possible molecular mechanism of castration resistance in prostate cancer , DRUG METABOLISM REVIEWS, 43, 23- 23, May. 2011,
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137 | A significant contribution of the organic cation/carnitine transporter, OCTN2, to tracheobronchial absorption of the anticholinergic bronchodilator, ipratropium , DRUG METABOLISM REVIEWS, 43, 82- 83, May. 2011,
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138 | Putative Transport Mechanism and Intracellular Fate of Trans-1-Amino-3-F-18-Fluorocyclobutanecarboxylic Acid in Human Prostate Cancer , JOURNAL OF NUCLEAR MEDICINE, 52( 5), 822- 829, May. 2011, https://doi.org/10.2967/jnumed.110.086074
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139 | Differential interaction of fruit juices with transporter-mediated absorption of drugs , DRUG METABOLISM REVIEWS, 43, 54- 54, May. 2011,
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140 |
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141 |
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142 | Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924 , MOLECULAR CANCER THERAPEUTICS, 10( 1), 117- 125, Jan. 2011, https://doi.org/10.1158/1535-7163.MCT-10-0438
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143 | Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans , DRUG METABOLISM AND DISPOSITION, 39( 1), 117- 122, Jan. 2011, https://doi.org/10.1124/dmd.110.035402
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144 | Intestinal Absorption of HMG-CoA Reductase Inhibitor Pitavastatin Mediated by Organic Anion Transporting Polypeptide and P-Glycoprotein/Multidrug Resistance 1 , DRUG METABOLISM AND PHARMACOKINETICS, 26( 2), 171- 179, 2011, https://doi.org/10.2133/dmpk.DMPK-10-RG-073
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145 | Carnitine Precursor gamma-Butyrobetaine is a Novel Substrate of the Na+- and Cl--dependent GABA Transporter Gat2 , DRUG METABOLISM AND PHARMACOKINETICS, 26( 6), 632- 636, 2011, https://doi.org/10.2133/dmpk.DMPK-11-NT-053
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146 | A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells , BIOCHEMICAL PHARMACOLOGY, 80( 11), 1754- 1761, Dec. 2010, https://doi.org/10.1016/j.bcp.2010.08.016
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147 | Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer , JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 122( 4), 180- 185, Oct. 2010, https://doi.org/10.1016/j.jsbmb.2010.06.014
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148 | Intestinal Absorption of HMG-CoA Reductase Inhibitor Pravastatin Mediated by Organic Anion Transporting Polypeptide , PHARMACEUTICAL RESEARCH, 27( 10), 2141- 2149, Oct. 2010, https://doi.org/10.1007/s11095-010-0216-5
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149 | Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: A possible target for combination therapy with anti-proliferative aminopeptidase inhibitors , BIOCHEMICAL PHARMACOLOGY, 80( 6), 811- 818, Sep. 2010, https://doi.org/10.1016/j.bcp.2010.05.021
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150 | Quantitative Visualization of Bile Canalicular Transporter Activity by Time-Lapse Imaging to Evaluate Drug-Drug Interaction in Sandwich-Cultured Hepatocytes , DRUG METABOLISM REVIEWS, 42, 290- 291, Aug. 2010,
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151 | Involvement of Choline Transporter-Like Proteins, CTL1 and CTL2, in Glucocorticoid-Induced Acceleration of Phosphatidylcholine Synthesis via Increased Choline Uptake , BIOLOGICAL & PHARMACEUTICAL BULLETIN, 33( 4), 691- 696, Apr. 2010, https://doi.org/10.1248/bpb.33.691
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152 | Side-population cells in luminal-type breast cancer have tumour-initiating cell properties, and are regulated by HER2 expression and signalling , BRITISH JOURNAL OF CANCER, 102( 5), 815- 826, Mar. 2010, https://doi.org/10.1038/sj.bjc.6605553
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153 | Renal Secretion of Uric Acid by Organic Anion Transporter 2 (OAT2/SLC22A7) in Human , BIOLOGICAL & PHARMACEUTICAL BULLETIN, 33( 3), 498- 503, Mar. 2010, https://doi.org/10.1248/bpb.33.498
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154 | Transport of Ipratropium, an Anti-Chronic Obstructive Pulmonary Disease Drug, Is Mediated by Organic Cation/Carnitine Transporters in Human Bronchial Epithelial Cells: Implications for Carrier-Mediated Pulmonary Absorption , MOLECULAR PHARMACEUTICS, 7( 1), 187- 195, Jan. 2010, https://doi.org/10.1021/mp900206j
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155 | Species Difference in the Effect of Grapefruit Juice on Intestinal Absorption of Talinolol between Human and Rat , JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 332( 1), 181- 189, Jan. 2010, https://doi.org/10.1124/jpet.109.159756
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156 | Impact of breast cancer resistance protein on cancer treatment outcomes. , Methods in molecular biology (Clifton, N.J.), 596, , 2010,
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157 |
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158 | Hepatic uptake of gamma-butyrobetaine, a precursor of carnitine biosynthesis, in rats , AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 297( 4), G681- G686, Oct. 2009, https://doi.org/10.1152/ajpgi.00238.2009
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159 | Role of OATP Transporters for Hepatic Uptake and Biliary Excretion of Beta-Lactam Antibiotics in Rats , DRUG METABOLISM REVIEWS, 41, 23- 23, Aug. 2009,
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160 | OATP-mediated Intestinal Absorption of HMG-COA Reductase Inhibitors in Rats , DRUG METABOLISM REVIEWS, 41, 24- 25, Aug. 2009,
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161 |
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162 |
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163 | Transport Characteristics of L-Citrulline in Renal Apical Membrane of Proximal Tubular Cells , BIOPHARMACEUTICS & DRUG DISPOSITION, 30( 3), 126- 137, Apr. 2009, https://doi.org/10.1002/bdd.653
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164 | Preclinical Studies of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytosine Arabinoside and Etoposide for Treatment of Acute Leukemias , CLINICAL CANCER RESEARCH, 15( 5), 1698- 1707, Mar. 2009, https://doi.org/10.1158/1078-0432.CCR-08-1587
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165 | Drug efflux by breast cancer resistance protein (BCRP) is a mechanism of resistance to the insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924. , Cancer Research, 69( 2), , 2009,
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166 | The 44-kDa pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells , JOURNAL OF BIOLOGICAL CHEMISTRY, 283( 6), 3349- 3356, Feb. 2008, https://doi.org/10.1074/jbc.M707773200
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167 |
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168 |
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169 | The overexpression of ERBB receptor tyrosine kinases and ABC transporters is associated with an increased side population in hormone resistant breast cancer cells , Breast Cancer Research and Treatment, 106, , 2007,
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170 | Breast cancer cells resistant to anti-hormone treatments retain sensitivity to Aminoflavone (NSC 686288) , Molecular Cancer Therapeutics, 6( 12), , 2007,
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171 | Erratum: Novel 5′ untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: Implications for drug resistance, tissue-specific expression, and alternative promoter usage (Cancer Research (2007) 66, (5007-5011)) , Cancer Research, 67( 9), , 2007, https://doi.org/10.1158/0008-5472.CAN-67-9-COR
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172 | Alterations in the mitochondrial Proteome of adriamycin resistant MCF-7 breast cancer cells , JOURNAL OF PROTEOME RESEARCH, 5( 9), 2389- 2395, Sep. 2006, https://doi.org/10.1021/pr060207c
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173 |
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174 | Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression , BLOOD, 108( 2), 678- 684, Jul. 2006, https://doi.org/10.1182/blood-2005-10-4020
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175 | Novel 5 ' untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: Implications for drug resistance, tissue-specific expression, and alternative promoter usage , CANCER RESEARCH, 66( 10), 5007- 5011, May. 2006, https://doi.org/10.1158/0008-5472.CAN-05-4572
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176 |
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177 | The ErB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102( 28), 9890- 9895, Jul. 2005, https://doi.org/10.1073/pnas.0503829102
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178 | Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors , CANCER CHEMOTHERAPY AND PHARMACOLOGY, 55( 2), 101- 109, Feb. 2005, https://doi.org/10.1007/s00280-004-0866-2
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179 |
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180 | Breast cancer resistance protein (BCRP/MXR/ABCG2) in adult acute lymphoblastic leukaemia: frequent expression and possible correlation with shorter disease-free survival , BRITISH JOURNAL OF HAEMATOLOGY, 127( 4), 392- 398, Nov. 2004, https://doi.org/10.1111/j.1365-2141.2004.05211.x
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181 | Breast cancer resistance protein (BCRP/MXR/ABCG2) in acute myeloid leukemia: discordance between expression and function , LEUKEMIA, 18( 7), 1252- 1257, Jul. 2004, https://doi.org/10.1038/sj.leu.2403395
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182 | The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme , JOURNAL OF BIOLOGICAL CHEMISTRY, 279( 23), 24218- 24225, Jun. 2004, https://doi.org/10.1074/jbc.M313599200
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183 |
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184 | Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the Oocytes of Xenopus laevis , MOLECULAR PHARMACOLOGY, 64( 6), 1452- 1462, Dec. 2003, https://doi.org/10.1124/mol.64.6.1452
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185 | Quantitative analysis of breast cancer resistance protein and cellular resistance to flavopiridol in acute leukemia patients , CLINICAL CANCER RESEARCH, 9( 9), 3320- 3328, Aug. 2003,
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186 | Timed sequential therapy of acute leukemia with flavopiridol: In vitro model for a phase I clinical trial , CLINICAL CANCER RESEARCH, 9( 1), 307- 315, Jan. 2003,
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187 | BCRP expression is regulated by hypoxia and provides a hypoxic survival advantage , Drug Metabolism Reviews, 35, 5- 5, 2003,
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188 | Breast cancer resistance protein expression and function in adult acute lymphoblastic leukemia. , Blood, 102( 11), , 2003,
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189 | Transport of D-serine via the amino acid transporter ATB(0,+) expressed in the colon , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 291( 2), 291- 295, Feb. 2002, https://doi.org/10.1006/bbrc.2002.6441
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190 | Evaluation of Blood-Brain Barrier Transporters by Co-culture of Brain Capillary Endothelial Cells with Astrocytes , Drug Metabolism and Pharmacokinetics, 17( 1), 34- 41, 2002, https://doi.org/10.2133/dmpk.17.34
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191 | Breast cancer resistance protein: Discordance between expression and function in acute myeloid leukemia. , Blood, 100( 11), , 2002,
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192 | Cloning and functional characterization of a new subtype of the amino acid transport system N , AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 281( 6), C1757- C1768, Dec. 2001,
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193 | Na+- and Cl--coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B-0,B-+ , JOURNAL OF CLINICAL INVESTIGATION, 107( 8), 1035- 1043, Apr. 2001, https://doi.org/10.1172/JCI12060
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194 | Na+- and Cl- -coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes , JOURNAL OF PHYSIOLOGY-LONDON, 532( 2), 297- 304, Apr. 2001, https://doi.org/10.1111/j.1469-7793.2001.0297f.x
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195 | Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 281( 5), 1343- 1348, Mar. 2001, https://doi.org/10.1006/bbrc.2001.4504
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196 | Na+- and Cl- -coupled transport of carnitine by the amino acid transporter ATB(0,+). , Faseb Journal, 15( 4), , 2001,
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197 | Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle , BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1509( 1-2), 7- 13, Dec. 2000, https://doi.org/10.1016/S0005-2736(00)00349-7
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198 |
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199 | Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter , JOURNAL OF BIOLOGICAL CHEMISTRY, 275( 31), 23707- 23717, Aug. 2000, https://doi.org/10.1074/jbc.M002282200
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200 | Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A , JOURNAL OF BIOLOGICAL CHEMISTRY, 275( 22), 16473- 16477, Jun. 2000, https://doi.org/10.1074/jbc.C000205200
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201 | A new orally active antitumor 1R,2R-cyclohexanediamine-platinum(IV) complex: trans-(n-valerato)chloro(1R,2R-cyclohexanediamine)(oxalato)platinum(IV) , CANCER CHEMOTHERAPY AND PHARMACOLOGY, 43( 2), 97- 105, Feb. 1999,
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202 | A new orally active antitumor 1R,2R-cyclohexanediamine-platinum(IV) complex: Trans-(n-valerato)chloro(1R,2R-cyclohexanediamine) (oxalato)platinum(IV) , Cancer Chemotherapy and Pharmacology, 43( 2), 97- 105, 1999, https://doi.org/10.1007/s002800050869
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203 | Improvement of L-dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1 , JOURNAL OF PHARMACEUTICAL SCIENCES, 87( 12), 1542- 1546, Dec. 1998, https://doi.org/10.1021/js980186o
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204 | Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 250( 2), 246- 251, Sep. 1998, https://doi.org/10.1006/bbrc.1998.9298
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205 | Significance of water solubility in the gastrointestinal absorption of trans-bis(n-valerato)(1R,2R-cyclohexanediamine)(oxalato)platinum(IV), an orally active antitumor platinum complex, and its analogs , ANTI-CANCER DRUGS, 9( 2), 167- 174, Feb. 1998,
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206 | Utilization of oligopeptide transporter for tissue specific drug delivery , Proceedings of the Controlled Release Society, ( 25), , 1998,
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207 | Carrier-mediated transport of oligopeptides in the human fibrosarcoma cell line HT1080 , CANCER RESEARCH, 57( 18), 4118- 4122, Sep. 1997,
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208 | The predominant contribution of oligopeptide transporter PepT1 to intestinal absorption of beta-lactam antibiotics in the rat small intestine , JOURNAL OF PHARMACY AND PHARMACOLOGY, 49( 8), 796- 801, Aug. 1997, https://doi.org/10.1111/j.2042-7158.1997.tb06115.x
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209 |
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210 | Immunolocalization and pharmacological relevance of oligopeptide transporter PepT1 in intestinal absorption of beta-lactam antibiotics , FEBS LETTERS, 392( 1), 25- 29, Aug. 1996, https://doi.org/10.1016/0014-5793(96)00778-8
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211 | An orally active antitumor cyclohexanediamine-Pt(IV) complex: trans,cis,cis-bis(n-valerato)(oxalato)(1R,2R-cyclohexanediamine)Pt(IV) , ANTI-CANCER DRUGS, 7( 3), 248- 256, May. 1996,
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Conference Activities & Talks |
No. | Title, Conference, Publication date, Promoter, Venue
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1 | Unappreciated roles of organic anion transporting polypeptides (OATPs) in human diseases, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center Hormone-Responsive Cancer Program Special Seminar, Mar. 15, 2017, Hormone-Responsive Cancer Program, Baltimore, MD, USA
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2 | 肺線維症モデルを用いた炎症におけるプロスタグランジン輸送体OATP2A1の役割の検討, 第38回生体膜と薬物の相互作用シンポジウム, Nov. 16, 2016, 日本薬学会, 名古屋
|
3 | Attenuation of endotoxin-induced fever in prostaglandin transporter OATP2A1 global and macrophage-specific knockout mice., , Nov. 9, 2016, , Lawrence, KS, USA
|
4 | Involvement of intestinal transporter OATP2B1 in gastrointestinal toxicity induced by SN-38, an active metabolite of anticancer irinotecan, , Nov. 9, 2016, , Lawrence, KS, USA
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5 | 炎症性疾患におけるプロスタグランジントランスポーターの新規役割, 日本薬物動態学会31年会, Oct. 15, 2016, 日本薬物動態学会, 松本
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6 | Alteration in PGE2 cellular disposition in murine macrophages by impaired function of prostaglandin transporter OATP2A1, , Oct. 14, 2016, ,
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7 | Evaluation of Food-induced Effect on Intestinal Drug Disposition, , Oct. 14, 2016, ,
|
8 | Possible increase of serum creatinine levels by crizotinib due to inhibition of creatinine transporters, , Oct. 14, 2016, ,
|
9 | Possible increase of serum creatinine levels by crizotinib due to inhibition of creatinine transporters, , Oct. 14, 2016, ,
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10 | Alteration in PGE2 disposition by subcellular localization of prostaglandin transporter,OATP2A1/SLCO2A1, The 21st International Symposium on Microsomes and Drug Oxidations, Oct. 2016, , Davis, CA, USA
|
11 | Alteration in PGE2 disposition by subcellular localization of prostaglandin transporter,OATP2A1/SLCO2A1, The 21st International Symposium on Microsomes and Drug Oxidations, Oct. 2016, , Davis, CA, USA
|
12 | Pathophysiological role of prostaglandin transporter OATP2A1/SLCO2A1 in pulmonary fibrosis, Workshop on Drug Transporters in the Lungs, Sep. 23, 2016, , Dlubin
|
13 | Role of Prostaglandin Transporter OATP2A1 in Inflammatory Phase in Bleomycin-induced Pulmonary Fibrosis, The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics, Jun. 24, 2016, Forum for Pharmaceutical Technology Inovation, Kyoto
|
14 | Prostaglandin Transporter OATP2A1 Contributes to PGE2 Secretion from Macrophages in Response to Inflammatory Stimulation, The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics, Jun. 24, 2016, Forum for Pharmaceutical Technology Inovation, Kyoto
|
15 | Inflammatory Fever Induced by LPS is Attenuated in Macrophage Specific OATP2A1 Knockout (Mφ-Slco2a1-/-) Mice, The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics, Jun. 24, 2016, Forum for Pharmaceutical Technology Inovation, Kyoto
|
16 | Unappreciated role of prostaglandin transporter OATP2A1 in inflammatory diseases, The 11th International Meeting of the International Society for the Study of Xenobiotics, Jun. 15, 2016, ISSX, Seoul
|
17 | 肝OATP/Oatp上での薬物間相互作用を予測する内因性プローブとしてのDehydroepiandrosterone sulfate (DHEAS) の有用性評価, 日本薬学会第136年会, Mar. 27, 2016, 日本薬学会, 横浜
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18 | プロスタグランジン輸送体 Slco2a1遺伝子欠損マウスにおけるリポ多糖誘発性体温上昇の抑制, 日本薬学会第136年会, Mar. 27, 2016, 日本薬学会, 横浜
|
19 | ブレオマイシン誘導性肺線維症モデル炎症期におけるプロスタグランジン輸送体OATP2A1の役割, 日本薬学会第136年会, Mar. 27, 2016, 日本薬学会, 横浜
|
20 | Impact of breast cancer resistance protein (BCRP/ABCG2) on chemotherapy; its function and gene regulation in cancer cells., 45th Annual Meeting of The Korean Society of Pharmaceutical Sciences and Technology (KSPST), Nov. 20, 2015, The Korean Society of Pharmaceutical Sciences and Technology (KSPST), Seoul, Korea
|
21 | OATP2B1によるSN-38の消化管動態調節を利用する消化器毒性回避法に関する研究, 第37回生体膜と薬物の相互作用シンポジウム, Nov. 19, 2015, 日本薬学会, 熊本
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22 | OATP2A1のプロスタグランジンE2動態調節を介した炎症制御に関する研究, 第37回生体膜と薬物の相互作用シンポジウム, Nov. 19, 2015, 日本薬学会, 熊本
|
23 | コーヒー摂取が及ぼす消化管BCRP輸送活性上昇機構と尿酸・薬物動態への影響, 第37回生体膜と薬物の相互作用シンポジウム, Nov. 19, 2015, 日本薬学会, 熊本
|
24 | スタチン誘発性骨格筋毒性バイオマーカーとしてのmicroRNAの探索, 日本薬学会北陸支部第127回例会, Nov. 15, 2015, 日本薬学会, 富山
|
25 | FDA承認薬ライブラリを用いたプロスタグランジントランスポーターOATP2A1の阻害剤探索, 日本薬学会北陸支部第127回例会, Nov. 15, 2015, 日本薬学会, 富山
|
26 | A modeling of cellular disposition of external 5-aminolevlulinic acid (ALA)-induced protoporphyrin IX (PPIX) for photodynamic cancer therapy, 日本薬物動態学会30年会, Nov. 13, 2015, 日本薬物動態学会, 東京
|
27 | Involvement of OATP2B1-mediated accumulation of SN-38 in enterocytes for irinotecan-derived gastrointestinal toxicity, 日本薬物動態学会30年会, Nov. 12, 2015, 日本薬物動態学会, 東京
|
28 | miR-24 regulates expression and function of human OATP2B1, 日本薬物動態学会30年会, Nov. 12, 2015, 日本薬物動態学会, 東京
|
29 | Pyrogenic effect of endotoxin is attenuated in organic anion transporting polypeptide (OATP) 2A1 knockout (Slco2a1-/-) mice, 日本薬物動態学会30年会, Nov. 12, 2015, 日本薬物動態学会, 東京
|
30 | Hyperuricemina-induced endothelial dysifunction by non-linear down-regulation of BCRP, 日本薬物動態学会30年会, Nov. 12, 2015, 日本薬物動態学会, 東京
|
31 | Evaluation of microRNA associated with statin-induced skeletal muscle toxicity, 日本薬物動態学会30年会, Nov. 12, 2015, 日本薬物動態学会, 東京
|
32 | Role of Breast Cancer Resistance Protein (BCRP/ABCG2) in Multidrug Resistance and Its Gene Expression in Cancer Cells, 4th Guangzhou International Symposium on Oncology, Nov. 6, 2015, Guangzhou International Symposium on Oncology, Guangzhou, China
|
33 | スタチン誘発性骨格筋毒性発症に関わるmicroRNAの探索, 第42回日本毒性学会学術年会, Jun. 30, 2015, , 金沢
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34 | プロスタグランジン輸送体OATP2A1は肺を線維症から保護する, 第10回トランスポーター研究会・中堅若手シンポジウム, Jun. 21, 2015, トランスポーター研究会, 慶応大学芝キャンパス、東京
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35 | BCRP機能低下による尿酸の血管内皮細胞障害作用, 第10回トランスポーター研究会年会, Jun. 21, 2015, , 東京
|
36 | Pathophysiological significance of organic anion transporting polypeptide (OATP), , May. 6, 2015, ,
|
37 | 有機アニオン輸送ポリペプチドOATPの病態生理学的意義, 富山大学大学院医学薬学研究部 特別講義, Apr. 23, 2015, 富山大学大学院医学薬学研究部, 富山大学杉谷キャンパス、富山
|
38 | 大腸癌の増殖におけるプロスタグランジン輸送体PGTの役割, 日本薬学会第135年, Mar. 26, 2015, 日本薬学会, 神戸
|
39 | プロスタグランジン輸送体機能欠損による肺線維症, 日本薬学会第135年, Mar. 26, 2015, 日本薬学会, 神戸
|
40 | Pathophysiological significance of prostaglandin transporter (PGT/SLCO2A1), 7th DMPK Forum in Kanazawa by Industry-Academia Collaboration, Mar. 11, 2015, Faculty of Pharmaceutical Sciences, Kanazawa University, 金沢
|
41 | 高尿酸血症によるBCRP輸送体活性低下が引き起こす血管障害促進メカニズム, 日本薬学会北陸支部第126回例会, Nov. 16, 2014, 日本薬学会, 金沢
|
42 | 小腸上皮薬物輸送体OATP2B1に及ぼすフルーツジュースの持続的阻害作用, 日本薬学会北陸支部第126回例会, Nov. 16, 2014, 日本薬学会, 金沢
|
43 | Prostaglandin transporter PGT responsible for regulating biological function of eicosapentaenoic acid-derived prostaglandin E3, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
|
44 | Possible involvement of OATP2B1 in gastrointestinal toxicity induced by SN-38, the active metabolite of anticancer irinotecan, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
|
45 | Prostaglandin transporter (PGT)-medaited PGE2 secretion from human corolectal cancer cells in response to oxidative stress, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
|
46 | Are uptake transporters involved in membrane transport process of anticoagulant drugs?, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
|
47 | Uremic toxins enhance BCRP-mediated intestinal urate secretion in Caco-2 cells, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
|
48 | Localization of transporter and enzymes regulating prostaglandin E2 level in mouse placenta, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
|
49 | Hepatocyte-based mathematical modeling reveals a novel metabolic pathway of bosentan in human liver, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
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50 | Increase of risk of acute renal failure and serum creatinine level by use of piperacillin/tazobactam, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
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51 | Relevance of prostaglandin transporter (PGT) to PGE2 secretion from macrophages in response to inflammatory stimulation, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
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52 | Effect of fruit juices on intestinal drug transporter, PEPT1, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
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53 | Biphasic Hepatic Uptake of Gemcitabine Characterized by Contribution of ENT1 and ENT2, 19th North American ISSX and 29th JSSX Meeting, Oct. 19, 2014, ,
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54 | プロスタグランジン輸送体PGTを標的する新しい薬物治療, 創剤フォーラム・第20回シンポジウム, Sep. 19, 2014, 創剤フォーラム, 金沢
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55 | がん細胞に発現するトランスポーターと化学療法, 第22回クリニカルファーマシーシンポジウム・医療薬学フォーラム2014, Jun. 29, 2014, 日本薬学会, 東京
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56 | 輸送体による薬物および内因性物質の肺動態調節, 日本薬剤学会第29年会, May. 20, 2014, 日本薬剤学会, 大宮
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57 | 大腸癌由来LoVo細胞におけるPGTを介したPGE2調節, 日本薬学会第134年会, Mar. 29, 2014, 日本薬学会, 熊本
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58 | アンドロゲン受容体陽性前立腺がん細胞の増殖におけるOATPの役割, 第7回 次世代を担う若手医療薬科学シンポジウム, Nov. 22, 2013, 日本薬学会, 仙台
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59 | 抗がん剤の多剤耐性予測における99mTcイメージング製剤の腫瘍細胞外排泄機構, 第53回日本核医学会学術総会, Nov. 8, 2013, 日本核医学会,
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60 | More relevant prediction for in vivo drug interaction of candesartan cilexetil on hepatic bile acid transporter BSEP using sandwich-cultured hepatocytes, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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61 | A possible enhanced effect of coffee constituents on intestinal urate excretion via BCRP, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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62 | A role of prostaglandin transporter PGT (OATP1A2) to adjusting pulmonary PGE2 level, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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63 | Negative transcriptional regulation of organic anion transporting polypeptide (OATP) 1A2 in androgen receptor (AR)-positive prostate cancer cells, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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64 | Involvement of renal reabsorptive transporters in insulin-dependent increase of serum uric acid, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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65 | An animal model for role of prostaglandin transporter (PGT) in biological function of prostaglandins, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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66 | Mechanism of a long-lasting inhibitory effect of apple juice on intestinal uptake transporter OATP2B1, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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67 | Improvement of intestinal absorption of anti-viral guanidine oseltamivir carboxylate (GOC) mediated by transporters, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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68 | Structural identification of multiple binding sites on OATP2B1, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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69 | Possibility of ZOSIN-induced elevation of serum creatine level due to specific interaction on creatinine transporters without renal failure, 日本薬物動態学会28年会, Oct. 9, 2013, 日本薬物動態学会, 東京
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70 | Mathematical modeling of in vitro hepatic disposition of mycophenolic acid and its glucuronide in sandwich-cultured human hepatocytes, 10th International ISSX Meeting, Sep. 29, 2013, ISSX, Toronto, Canada
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71 | Impact of OATP2B1 expression on cell proliferation in ER-positive breast cancer, 10th International ISSX Meeting, Sep. 29, 2013, ISSX, Toronto, Canada
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72 | Lasting inhibition of intestinal absorptive transporter OATP2B1 by fruits juice, 10th International ISSX Meeting, Sep. 29, 2013, ISSX, Toronto, Canada
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73 | 消化管トランスポーターを利用した吸収改善のストラテジー, 第29回日本DDS学会学術集会, Jul. 5, 2013, 日本DDS学会, 京都
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74 | 薬物動態・個体差要因可視化による個別化EBM(Evidence・Based・Medicine)の推進, 第29回日本DDS学会学術集会, Jul. 4, 2013, 日本DDS学会, 京都
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75 | Transport mechanism of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid (18F-FACBC)PET radiotracer in human prostate cancer, The Society of Nuclear Medicine and Molecular Imaging's (SNMMI) 2013 Annual Meeting, Jun. 11, 2013, The Society of Nuclear Medicine and Molecular Imaging, Vancouver, Canada
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76 | 血管内皮細胞における尿酸輸送体を介した酸化ストレス調節, 第46回日本痛風・核酸代謝学会総会, Feb. 14, 2013, 日本痛風・核酸代謝学会, 東京
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77 | Transporter as an emerging target for cancer therapy, 日本薬物動態学会第27年会, Nov. 21, 2012, 日本薬物動態学会, 東京
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78 | Substrate-dependent drug-grapefruit juice interactions caused by multiple binding sites on OATP2B1, 日本薬物動態学会27年会, Nov. 20, 2012, 日本薬物動態学会, 東京
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79 | OATP transporters is involved in intestinal absorption of urate, , Nov. 20, 2012, ,
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80 | A role of prostaglandin transporter in regulating PGE2 release from human bronchial BEAS-2B cells under inflammatory conditions, 日本薬物動態学会27年会, Nov. 20, 2012, 日本薬物動態学会, 東京
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81 | In vitro evidence for functional interplay of SMCT1 and URAT1 for renal reabsorption of urate, 日本薬物動態学会27年会, Nov. 20, 2012, 日本薬物動態学会, 東京
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82 | Role of OCTN1 in ergothioneine cytoprotection against oxaliplatin toxicity in OCTN1 over-expressing HEK293 cells and cultured rodent dorsal root ganglion neurons, 日本薬物動態学会27年会, Nov. 20, 2012, 日本薬物動態学会, 東京
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83 | Effect of drugs on renal urate reabsorption: evaluation by URAT1/URATv1 co-expressing cells, 日本薬物動態学会27年会, Nov. 20, 2012, 日本薬物動態学会, 東京
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84 | Long-lasting effect of fruit juice on intestinal absorptive transporter OATP2B1, , Nov. 20, 2012, ,
|
85 | Application of quantitative time-lapse imaging (QTLI) for evaluation of MRP2/MRP2-based drug-drug interaction in rat and human hepatocytes, , Nov. 20, 2012, ,
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86 | A role of prostaglandin transporter in regulation of intercellular PGE2 levels under inflammatory conditions, , Nov. 2012, ,
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87 | In vitro evidence for functional interplay of SMCT1 and URAT1 for renal reabsorption of urate, , Sep. 2012, ,
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88 | Enhanced carrier mediated transport: improving oral absorption of BCS Class Ⅲ antiviral drugs., 第28回日本DDS学会学術集会, Jul. 4, 2012, 日本DDS学会, 札幌
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89 | 肝代謝を考慮した蛍光イメージング(QTLI)法によるMRP2上での薬物間相互作用予測, 日本薬剤学会27年会, May. 24, 2012, 日本薬剤学会, 神戸
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90 | ABC輸送体上での薬物相互作用に起因するDonepezilの心毒性リスク, 日本薬剤学会30年会, May. 24, 2012, 日本薬剤学会, 長崎
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91 | 前立腺癌細胞におけるトランスポーターを介したアンドロゲン供給調整機構の解明, 日本薬剤学会27年会, May. 24, 2012, 日本薬剤学会, 神戸
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92 | Transporters as targets for drug delivery and therapy, , Apr. 17, 2012, ,
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93 | URAT1/URATv1共発現細胞を用いたin vitro尿酸再吸収性変動評価, , Feb. 17, 2012, , 奈良
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94 | BCRPを介した尿酸の腸管腔内分泌特性, 第45回日本痛風・核酸代謝学会総会, Feb. 17, 2012, 日本痛風・核酸代謝学会, 奈良
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95 | トランスポーターを介した薬物—ジュース間相互作用機構, 日本薬学会北陸支部第123回例会, Nov. 29, 2011, 日本薬学会, 金沢
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96 | ヒトがん細胞における5-アミノレブリン酸 (ALA) 誘導性プロトポルフィリンⅨ蓄積機構の解明, 日本薬学会北陸支部第123回例会, Nov. 29, 2011, 日本薬学会, 金沢
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97 | In vitroイメージング (QTLI) 法を用いたMRP2機能変動評価 —肝代謝を考慮した薬物相互作用予測への応用—, 日本薬学会北陸支部第123回例会, Nov. 29, 2011, 日本薬学会, 金沢
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98 | Upregulation of organic anion transporting polypeptides (OATPs) under the androgen-depletion conditions; A possible molecular mechanism for castration resistance in prostate cancer, , Nov. 16, 2011, ,
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99 | In vitro evaluation model for renal reabsorption of uric acid: establishment of cells coexpressing URAT1 and URATv1, , Nov. 16, 2011, ,
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100 | Evaluation of determinants factors for accumulation of 5-amminolevulinic acid (ALA)-induced protoporphyrin IX in cancer cells, , Nov. 16, 2011, ,
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101 | Intestinal active secretion of uric acidcer, , Nov. 16, 2011, ,
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102 | Functional pleiotropy of OATP2B1 due to multiple binding sites, , Nov. 16, 2011, ,
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103 | Variability of juice-drug interaction in absorption process caused by multiple binding sites on OATP2B1, , Nov. 16, 2011, ,
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104 | イプラトロピウムの気道上皮細胞膜透過における有機カチオントランスポーターの関与, 日本薬剤学会26年会, May. 29, 2011, 日本薬剤学会, 東京
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105 | Side population cells with tumor-initiating cells properties are regulated by HER2 signaling in luminal-type breast cancer, 第11回春季シンポジウム金沢国際がん生物学シンポジウム, May. 26, 2011, 日本分子生物学会, 金沢
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106 | Differential interaction of fruit juices on transporter-mediated absorption of drugs, , Apr. 2011, ,
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107 | Upregulation of organic anion transporting polypeptide(OATP)1A2 by depletion of androgens; a possible molecular mechanism of castration resistance in prostate cancer., , Apr. 2011, ,
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108 | A Significant contribution of organic cation/carnitine transporter, OCTN2, to tracheobronchial absorption of anti-cholinergic bronchodilator, ipratropium, , Apr. 2011, ,
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109 | ラットにおける尿酸の腎外排泄機構, 第44回日本痛風・核酸代謝学会総会, Feb. 17, 2011, 日本痛風・核酸代謝学会, 東京
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110 | イプラトロピウムの気道吸収における有機カチオン/カルニチントランスポーターの関与, 日本薬学会北陸支部第122回例会, Nov. 21, 2010, 日本薬学会, 金沢
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111 | Difference Interaction of grapefruit juice with intestinal absorption of HMG-CoA reductase inhibitors pravastatin and pitavastatin, , Nov. 2010, ,
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112 | Uric Acid Transporter-mediated uricosuric effect of RDEA594, a metabo I ite of antiviral agent RDEA806, , Nov. 2010, ,
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113 | Mechanism of extra-renal excretion of uric acid in rats, , Oct. 7, 2010, ,
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114 | Differential transporter-mediated interaction of fruit juice with pravastatin and pitavastatin in rats, , Oct. 7, 2010, ,
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115 | Differential interaction of fruit juices on transporter-mediated absorption of drugs, , Oct. 7, 2010, ,
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116 | System L-amino acid transporter 1 (LAT1) is a possible target for combination therapy with antiproliferative aminopeptidase inhibitors in human ovarian cancer cells., , Oct. 7, 2010, ,
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117 | Tracheal absorption of an anticholinergic bronchodilator ipratropium via organic cation transporters., , Oct. 7, 2010, ,
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118 | Differential expression of organic cation transporters in rat dorsal root ganglia, , Oct. 7, 2010, ,
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119 | Quantitative visualization for bile canalicular transporter function using sandwich-cultured rat hepatocytes, , Oct. 7, 2010, ,
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120 | Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer, , Sep. 2010, ,
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121 | ヒト癌細胞株におけるOAT2を介した光線力学療法薬5-アミノレブリン酸の細胞膜輸送, 日本薬剤学会25年会, May. 14, 2010, 日本薬剤学会, 徳島
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122 | がん標的分子としてのトランスポーターの可能性について, 大鵬薬品工業株式会社 特別講演, Mar. 5, 2010, 大鵬薬品工業株式会社, つくば市
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123 | Mechanism for hepatic uptake of γ-butyrobetaine, a precursor of carnitine biosynthesis, 第31回生体膜と薬物の相互作用シンポジウム, Nov. 30, 2009, 日本薬学会, 大阪
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124 | COPD治療薬の体内動態におけるトランスポーターの役割, 第32回生体膜と薬物の相互作用シンポジウム, Nov. 29, 2009, 日本薬学会, 富山
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125 | Visualization of transport activity by live-cell time-lapse imaging for evaluation of intracellular transporter function, 日本薬物動態学会24年会, Nov. 27, 2009, 日本薬物動態学会, 京都
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126 | Uric acid transporter-mediated uricosuric effect of RDEA594, a metabolite of antiviral agent RDEA806, 日本薬物動態学会24年会, Nov. 27, 2009, 日本薬物動態学会, 京都
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127 | Interaction of diuretics with uric acid transporter urat1 as one of causes of antiuricosuric effect, 日本薬物動態学会24年会, Nov. 27, 2009, 日本薬物動態学会, 京都
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128 | Regional difference of transporter-mediated absorption of drugs, 日本薬物動態学会24年会, Nov. 27, 2009, 日本薬物動態学会, 京都
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129 | Pulmonary absorption of ipratropium via transporters in cultured human bronchial epithelial cells., 日本薬物動態学会24年会, Nov. 27, 2009, 日本薬物動態学会, 京都
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130 | A molecular mechanism of hepatic uptake of gamma-butyrobetaine, a precursor of carnitine biosynthesis., , Nov. 27, 2009, ,
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131 | HER2 expands tumor-initiating breast cancer cells in the side population - implications for targeted intervention, , Nov. 27, 2009, ,
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132 | Relevance of organic cation transporter (OCT) 2 to renal secretion of ipratropium, , Nov. 27, 2009, ,
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133 | DRUG TRANSPORTERS AS TARGETS FOR DRUG DELIVERY AND CANCER CHEMOTHERAPY., Asian Federation for Pharmaceutical Sciences 2009, Oct. 2009, ,
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134 | Quantitative visualization of liver bile canalicular transporter activity by time-lapse imaging to evaluate drug-drug interaction in sandwich-cultured hepatocytes, , Sep. 2009, ,
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135 | Role of OATP transporters for hepatic uptake and billiary excretion of beta-lactam antibiotics in rats, , May. 2009, , Bangkok, Thailand
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136 | OATP-mediated intestinal absorption of HMG-CoA reductase inhibitors in rats, , May. 2009, , Bangkok, Thailand
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137 | Alternative promoter activity of the human breast cancer resistance protein (BCRP/ABCG2) gene in drug-resistant cancer cells, , Apr. 2007, ,
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138 | Overexpression of HER2/neu in breast cancer cell lines is associated with an increased side population, presence of ABC transporters, and clonogenicity, , Apr. 2007, ,
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139 | Identification and characterization of the major alternative promoter controlling Bcrp1/Abcg2 expression in the mouse intestine, , Apr. 2007, ,
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140 | Power-maximized experimental design and combination index surface analysis for evaluating interactions of drug combinations, with applications to suberoylanilide hydroxamic acid (SAHA) combined with etoposide (VP-16) in HL-60 human acute myeloid leukemia, , Apr. 2007, ,
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141 | Principal Bcrp1 (Breast cancer resistance protein) mRNA isoform in the mouse intestine: Identification and promoter characterization predominant, , Sep. 2006, ,
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142 | BCRP expression is functionally upregulated by epidermal growth factor receptor (EGFR, ErbB1) mediated signaling in human ovarian cancer cell lines, but not in human breast cancer cell lines, , Apr. 2006, ,
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143 | Schedule Dependent Synergy of Suberoylanilide Hydroxamic Acid (SAHA or Vorinostat) in Combination with Cytarabine (ara-C) and Etoposide in HL-60 Human Acute Myeloid Leukemia Cells, , Apr. 2006, ,
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144 | Complex interaction of BCRP/ABCG2 and STI-571 in BCR-ABL positive cells: BCRP-mediated resistance to STI-571 is attenuated by STI-571-induced reduction in BCRP expression, , Apr. 2005, ,
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145 | Evaluation of the Mechanism of BCRP/ABCG2 Gene Overexpression of in Drug-Selected Multidrug Resistant Cells, , Mar. 2004, ,
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146 | The stem cell marker (ABCG2) enhances hypoxic cell survival through interactions with heme, , Mar. 2004, ,
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147 | Breast Cancer Resistance Protein Expression and Function in Adult Acute Lymphoblastic Leukemia, , Dec. 2003, ,
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148 | Mechanisms of BCRP Overexpression in Drug-Selected Multidrug Resistant Cells, , Jul. 2003, ,
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149 | Functional characterization of human BCRP expressed in Xenopus laevis oocytes, , Jul. 2003, ,
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150 | The breast cancer resistance protein is upregulating by hypoxia and provides a survival advantage under hypoxic conditions, , Jul. 2003, ,
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151 | Breast cancer resistance protein: Discordance between expression and function in acute myeloid leukemia, , Dec. 2002, ,
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152 | Quantitative analysis of breast cancer protein (BCRP) and cellular resistance to flavopiridol in acute leukemia (AML) patients, American Association of Cancer Research, Apr. 2002, ,
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153 | Primary structure, genomic organization, and functional and electrogenic characteristics of human system N (SN1), a sodium- and proton-coupled glutamine transporter., , Jun. 2000, , Boston
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154 | Enforced expression and functional characterization of carnitine/organic anion transporter, OCTN2., 日本薬学会第120年会, Mar. 29, 2000, 日本薬学会, 岐阜
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155 | Molecular and functional identification of organic anion transporter OATP family members important for hepatic elimination of β-lactam antibiotics in human. International Conference on Drug Interaction., , Oct. 1999, ,
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156 | Cancer cell-targeted delivery of gestating by utilization of membrane transporter, , Sep. 29, 1999, ,
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157 | Features in molecular recognition and transports of ACE inhibitors by peptide transporter, PepT1., , Mar. 29, 1999, ,
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158 | トランスポーターの組織特異的な発現を利用した腫瘍組織ターゲティング戦略, 日本薬剤学会14年会, Mar. 26, 1999, 日本薬剤学会, 岡山
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159 | Molecular recognition mechanism of peptide transporter, PepT1., , Nov. 1998, ,
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160 | Characterization of oligopeptide transport activity in tumor cells and tumor specific drug delivery, , Oct. 1998, ,
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161 | Utilization of oligopeptide transporter for tissue specific drug delivery, , Jun. 1998, , Las Vegas, NV, USA
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162 | ペプチドトランスポーターPepT1に対する基質の阻害・輸送間相関, 日本薬剤学会13年会, Mar. 25, 1998, , 甲府
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163 | ペプチド輸送系を利用した薬物の腫瘍組織ターゲティング, 日本薬剤学会13年会, Mar. 25, 1998, ,
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164 | Studies for transporter-mediated targeting of tumor tissue using cultured cell lines., 日本薬学会第118年会, Mar. 1998, , 京都
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165 | 新規抗腫瘍性ヌクレオシドの細胞膜透過性, 日本薬物動態学会12年会, Nov. 4, 1997, ,
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166 | オリゴペプチド輸送系の基質認識特性を利用した組織選択的薬物デリバリーは可能か., , Nov. 4, 1997, ,
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167 | Research and development of orally active antitumor platinum complexes, - Anti-tumor activities and pharmacokinetics of oxaliplatin derivatives -, Symposium for biological reactions involved in metals, Jun. 1995, ,
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168 | Research and development of orally active antitumor platinum complexes - Pharmacokinetics of trans, cis, ci-bis (velerato) (1R, 2R-cycolohexaanediamine)(oxalato)Pt(IV)-, , Mar. 1995, 日本薬学会,
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169 | Unappreciated roles of organic anion transporting polypeptides (OATPs) in human diseases, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center Hormone-Responsive Cancer Program Special Seminar, Mar. 15, 1027, University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA
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170 | マクロファージからのPGE2開口分泌におけるプロスタグランジン輸送体の役割, 第56回日本脂質生化学会, , 日本脂質生化学会,
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171 | 腫瘍細胞におけるペプチドトランスポート活性とペプチド性抗癌剤の薬効発現, 日本薬物動態学会13年会, , 日本薬物動態学会, 浜松
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172 | Improvement of Intestinal Absorption and Tissue Targeting of peptide-mimetic drugs by utilization of oligopeptide transporter, , , ,
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173 | The overexpression of ERBB receptor tyrosine kinases and ABC transporters is associated with an increased side population in hormone resistant breast cancer cells., , , ,
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174 | Breast Cancer Resistance Protein (BCRP, ABCG2) Transcriptional Upregulation in Drug-Selected Cells Bypasses the Physiologic Promoter, , , ,
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175 | Evaluation of the Function of Breast Cancer Resistance Protein (BCRP/ABCG) Expressed in Xenopus Laevis Oocytes, , , ,
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176 | Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A., , , ,
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177 | 第8回ライフサイエンス研究交流セミナー, , , ,
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178 | Selective delivery of peptide anticancer drugs via oligopeptide transporter expressed in cancer cells, , , ,
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