Takasaki University of Health and Welfare

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OUMOTO Makoto

Profile Research field Research achievement Educational achievement Management achievement Social contribution achievement

 

Published Papers
No.Title URL, Journal, Vol( No), Start Page- End Page, Publication date, DOI 
1
A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells , eneuro, 10( 4), ENEURO.0236- 22.2023, Apr. 12, 2023, https://doi.org/10.1523/eneuro.0236-22.2023 
2
Maintenance and turnover of Sox2+ adult stem cells in the gustatory epithelium , PLOS ONE, 17( 9), e0267683- e0267683, Sep. 2, 2022, https://doi.org/10.1371/journal.pone.0267683 
3
Expression of Eya1 in mouse taste buds. , Cell and tissue research, 383( 3), 979- 986, Mar. 2021, https://doi.org/10.1007/s00441-020-03311-9 
4
R-spondin substitutes for neuronal input for taste cell regeneration in adult mice , Proceedings of the National Academy of Sciences, 118( 2),  , Dec. 28, 2020, https://doi.org/10.1073/pnas.2001833118 
5
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. , Gastroenterology, 159( 5), 1866- 1881, Nov. 2020, https://doi.org/10.1053/j.gastro.2020.07.037 
6
Sodium–Taste Cells Require Skn-1a for Generation and Share Molecular Features with Sweet, Umami, and Bitter Taste Cells , eneuro, 7( 6), ENEURO.0385- 20.2020, Nov. 2020, https://doi.org/10.1523/eneuro.0385-20.2020 
7
SOX2 regulates homeostasis of taste bud cells and lingual epithelial cells in posterior tongue. , PloS one, 15( 10), e0240848- , 2020, https://doi.org/10.1371/journal.pone.0240848 
8
Bcl11b controls odorant receptor class choice in mice. , Communications biology, 2( 1), 296- , 2019, https://doi.org/10.1038/s42003-019-0536-x 
9
CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes. , Neuron, 98( 3), 547- 561, May. 2, 2018, https://doi.org/10.1016/j.neuron.2018.03.043 
10
Activation of intestinal tuft cell-expressed sucnr1 triggers type 2 immunity in the mouse small intestine , Proceedings of the National Academy of Sciences of the United States of America, 115,  5552- 5557, May. 2018, https://doi.org/10.1073/pnas.1720758115 
11
Skn-1a/Pou2f3 functions as a master regulator to generate Trpm5-expressing chemosensory cells in mice , PLOS ONE, 12( 12),  , Dec. 2017, https://doi.org/10.1371/journal.pone.0189340 
12
Genetic Lineage Tracing in Taste Tissues Using Sox2-CreERT2 Strain , CHEMICAL SENSES, 42( 7), 547- 552, Sep. 2017, https://doi.org/10.1093/chemse/bjx032 
13
Bcl11b/Ctip2 is required for development of lingual papillae in mice , DEVELOPMENTAL BIOLOGY, 416( 1), 98- 110, Aug. 2016, https://doi.org/10.1016/j.ydbio.2016.06.001 
14
CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice , SCIENTIFIC REPORTS, 6,   , Apr. 2016, https://doi.org/10.1038/srep24250 
15
Expression of serotonin receptor genes in cranial ganglia , NEUROSCIENCE LETTERS, 617,  46- 51, Mar. 2016, https://doi.org/10.1016/j.neulet.2016.01.050 
16
Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites , NATURE, 529( 7585), 226- U260, Jan. 2016, https://doi.org/10.1038/nature16527 
17
Normal Taste Acceptance and Preference of PANX1 Knockout Mice , CHEMICAL SENSES, 40( 7), 453- 459, Sep. 2015, https://doi.org/10.1093/chemse/bjv025 
18
Expression of the synaptic exocytosis-regulating molecule complexin 2 in taste buds and its participation in peripheral taste transduction , JOURNAL OF NEUROCHEMISTRY, 133( 6), 806- 814, Jun. 2015, https://doi.org/10.1111/jnc.13073 
19
Genetics of taste receptors , Current Pharmaceutical Design, 20,  2669- 2683, Jan. 2014, https://doi.org/10.2174/13816128113199990566 
20
Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium , BMC NEUROSCIENCE, 15,   , Jan. 2014, https://doi.org/10.1186/1471-2202-15-13 
21
Transgenic labeling of higher order neuronal circuits linked to phospholipase C-β2-expressing taste bud cells in medaka fish , Journal of Comparative Neurology, 521( 8), 1781- 1802, Jun. 1, 2013, https://doi.org/10.1002/cne.23256 
22
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes , NATURE, 495( 7440), 223- 226, Mar. 2013, https://doi.org/10.1038/nature11906 
23
Differential expression analysis throughout the weaning period in the mouse cerebral cortex , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 431( 3), 437- 443, Feb. 2013, https://doi.org/10.1016/j.bbrc.2012.12.150 
24
Functional diversification of taste cells in vertebrates , Seminars in Cell and Developmental Biology, 24( 3), 210- 214, 2013, https://doi.org/10.1016/j.semcdb.2012.10.004 
25
Pou2f3/Skn-1a is necessary for the generation or differentiation of solitary chemosensory cells in the anterior nasal cavity , Bioscience, Biotechnology and Biochemistry, 77( 10), 2154- 2156, 2013, https://doi.org/10.1271/bbb.130454 
26
ACCUMULATION OF SNAP25 IN MOUSE GUSTATORY AND SOMATOSENSORY CORTICES IN RESPONSE TO FOOD AND CHEMICAL STIMULATION , NEUROSCIENCE, 218,  326- 334, Aug. 2012, https://doi.org/10.1016/j.neuroscience.2012.05.045 
27
Genetic tracing of the gustatory neural pathway originating from Pkd1l3-expressing type III taste cells in circumvallate and foliate papillae , JOURNAL OF NEUROCHEMISTRY, 119( 3), 497- 506, Nov. 2011, https://doi.org/10.1111/j.1471-4159.2011.07443.x 
28
Bcl11b/Ctip2 Controls the Differentiation of Vomeronasal Sensory Neurons in Mice , JOURNAL OF NEUROSCIENCE, 31( 28), 10159- 10173, Jul. 2011, https://doi.org/10.1523/JNEUROSCI.1245-11.2011 
29
Mutually Exclusive Expression of G alpha ia and G alpha 14 Reveals Diversification of Taste Receptor Cells in Zebrafish , JOURNAL OF COMPARATIVE NEUROLOGY, 519( 8), 1616- 1629, Jun. 2011, https://doi.org/10.1002/cne.22589 
30
Skn-1a (Pou2f3) specifies taste receptor cell lineage , NATURE NEUROSCIENCE, 14( 6), 685- 687, Jun. 2011, https://doi.org/10.1038/nn.2820 
31
Genetic tracing of the neural pathway for bitter taste in t2r5-WGA transgenic mice , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 400( 4), 734- 738, Oct. 2010, https://doi.org/10.1016/j.bbrc.2010.08.139 
32
Spatial differences in molecular characteristics of the pontine parabrachial nucleus , BRAIN RESEARCH, 1296,  24- 34, Oct. 2009, https://doi.org/10.1016/j.brainres.2009.07.098 
33
Functional Organization of the Rodent Parabrachial Nucleus , INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE, 1170,  378- 382, 2009, https://doi.org/10.1111/j.1749-6632.2009.03883.x 
34
Genetic Tracing of the Gustatory Neural Pathway Originating from T1R3-expressing Sweet/Umami Taste Receptor Cells , INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE, 1170,  46- 50, 2009, https://doi.org/10.1111/j.1749-6632.2009.03932.x 
35
Genetic tracing of the gustatory and trigeminal neural pathways originating from T1R3-expressing taste receptor cells and solitary chemoreceptor cells , MOLECULAR AND CELLULAR NEUROSCIENCE, 38( 4), 505- 517, Aug. 2008, https://doi.org/10.1016/j.mcn.2008.04.011 
36
Transgenic labeling of taste receptor cells in model fish under the control of the 5 '-upstream region of medaka phospholipase C-beta 2 gene , GENE EXPRESSION PATTERNS, 7( 1-2), 149- 157, Jan. 2007, https://doi.org/10.1016/j.modgep.2006.06.004 
37
Relation between acute and late irradiation impairment of four basic tastes and irradiated tongue volume in patients with head-and-neck cancer , INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 66( 5), 1422- 1429, Dec. 2006, https://doi.org/10.1016/j.ijrobp.2006.08.037 
38
Taste receptor cells express voltage-dependent potassium channels in a cell age-specific manner , CHEMICAL SENSES, 31( 8), 739- 746, Oct. 2006, https://doi.org/10.1093/chemse/bjl016 

 

Research Grants & Projects
No.Offer organization, System name, Title, Fund classification, Date 
1
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Function of taste bud cells other than sweet, umami, bitter, and sour taste receptor cells, ,  2009 - 2010