高崎健康福祉大学

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高崎健康福祉大学
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桑原 敦志 (クワバラ アツシ,KUWABARA Atsushi)

基本情報 研究分野 研究業績 教育業績 運営業績 社会貢献業績

 

論文
No.論文タイトル URL, 誌名(出版物名), 巻( 号), 開始ページ- 終了ページ, 出版年月, DOI 
1
Lipoprotein-associated lysolipids are differentially involved in high-density lipoprotein- and its oxidized form-induced neurite remodeling in PC12 cells , NEUROCHEMISTRY INTERNATIONAL, 68,  38- 47, 2014年03月, https://doi.org/10.1016/j.neuint.2014.02.005 
2
Mechanism and Role of High Density Lipoprotein-induced Activation of AMP-activated Protein Kinase in Endothelial Cells , JOURNAL OF BIOLOGICAL CHEMISTRY, 285( 7), 4387- 4397, 2010年02月, https://doi.org/10.1074/jbc.M109.043869 
3
LPA(1) receptors mediate stimulation, whereas LPA(2) receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites , CARCINOGENESIS, 30( 3), 457- 465, 2009年03月, https://doi.org/10.1093/carcin/bgp011 
4
HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 359( 3), 649- 654, 2007年08月, https://doi.org/10.1016/j.bbrc.2007.05.131 
5
Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells , AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 292( 5), H2513- H2522, 2007年05月, https://doi.org/10.1152/ajpheart.00865.2006 
6
Role of scavenger receptor class B type I and sphingosine 1-phosphate receptors in high density lipoprotein-induced inhibition of adhesion molecule expression in endothelial cells , JOURNAL OF BIOLOGICAL CHEMISTRY, 281( 49), 37457- 37467, 2006年12月, https://doi.org/10.1074/jbc.M605823200 

 

MISC
No.MISCタイトル URL, 誌名, 巻( 号), 開始ページ- 終了ページ, 出版年月(日) 
1
Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells.(共著) , Biochem J., 353( 1), 139- 146, 2001年 
2
Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions.(共著) , Biochem J., 352( 3), 809- 815, 2000年 
3
Sphingosine 1-phosphate stimulates insulin secretion in HIT-T 15 cells and mouse islets , Endocrine Journal, 47( 3), 261- 269, 2000年 
4
Involvement of circulating interleukin-6 and its receptor in the development of euthyroid sick syndrome in patients with acute myocardial infarction.(共著) , Eur J Endocrinol., 143( 2), 179- 184, 2000年 
5
Type IV collagen as an early marker for diabetic nephropathy in non-insulin-dependent diabetes mellitus.(共著) , J Diabetes Complications., 14( 1),  , 2000年 
6
Circulating interleukin-6 significantly correlates to thyroid hormone in acute myocardial infarction but not in chronic heart failure.(共著) , J Endocrinol Invest., 23( 8), 509- 514, 2000年 
7
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3.(共著) , Biochem J., 348( 1), 71- 76, 2000年 
8
Comparison of intrinsic activities of the putative sphingosine 1-phosphate receptor subtypes to regulate several signaling pathways in their cDNA-transfected Chinese hamster ovary cells.(共著) , J Biol Chem., 274( 34), 23940- 23947, 1999年 
9
Activation of phospholipase C-Ca2+ system by sphingosine 1-phosphate in CHO cells transfected with Edg-3, a putative lipid receptor.(共著) , FEBS Lett., 443( 1), 25- 30, 1999年 
10
Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells.(共著) , Biochem J., 336( Pt2), 491- 500, 1998年 
11
Participation of the pituitary-thyroid axis in the cardiovascular system in elderly patients with congestive heart failure.(共著) , J Med., 28( 1-2), 75- 80, 1997年 
12
Inhibition of TSH-induced hydrogen peroxide production by TNF-alpha through a sphingomyelinase signaling pathway.(共著) , Am J Physiol., 273( 3Pt1), E639-E643- , 1997年 
13
Untreated Graves' but not remission Graves' immunoglobulin G preparations increase intracellular Ca2+ in FRTL-5 thyroid cells.(共著) , Endocr J., 43( 5), 457- 467, 1996年 
14
Both cyclooxygenase and lipoxygenase inhibitor partially restore the anorexia by interleukin-1 beta.(共著) , Life Sci., 51( 18), 1419- 1426, 1992年 
15
Enhanced sensitivity to anorexia and consumption of drinking water induced by interleukin-1 beta in obese yellow mice.(共著) , Eur J Pharmacol., 209( (1-2)), 15- 18, 1991年 
16
Contemplation of age-adjusted standard values of lipid profiles in Japan.(共著) , J Med 2001 in press, ,   ,   

 

共同研究・競争的資金等の研究課題
No.提供機関, 制度名, 課題名等, 資金種別, 研究期間 
1
文部科学省, 科学研究費補助金基盤研究(C), リポ蛋白質の相反する作用の決定因子としてのリゾリン脂質シグナル分子。, 競争的資金,  2009年04月 - 2012年03月 
2
文部科学省, 科学研究費補助金基盤研究(C), 冠動脈心疾患の新しいバイオマーカーとしてのリポ蛋白中リゾリン脂質バランス変化。, 競争的資金,  2006年04月 - 2009年03月 
3
文部科学省, 科学研究費補助金基盤研究(C), 脂質性シグナル分子、スフィンゴシン1-リン酸の細胞外濃度変化と臨床診断への応用, 競争的資金,  2003年04月 - 2006年03月 
4
, , sphingosine 1-リン酸の血中分布, 競争的資金, 
5
, , Distribusin of sphingosine 1-phosphate in the blood., 競争的資金,